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B29806

1-Benzyl-4-piperidone

99%

Synonim(y):

1-Benzyl-4-oxopiperidine

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C12H15NO
Numer CAS:
Masa cząsteczkowa:
189.25
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
222-782-4
Beilstein/REAXYS Number:
128556
MDL number:
Assay:
99%
Form:
liquid


assay

99%

form

liquid

refractive index

n20/D 1.541 (lit.)

bp

134 °C/7 mmHg (lit.)

density

1.021 g/mL at 25 °C (lit.)

functional group

ketone, phenyl

storage temp.

2-8°C

SMILES string

O=C1CCN(CC1)Cc2ccccc2

InChI

1S/C12H15NO/c14-12-6-8-13(9-7-12)10-11-4-2-1-3-5-11/h1-5H,6-10H2

InChI key

SJZKULRDWHPHGG-UHFFFAOYSA-N

General description

1-Benzyl-4-piperidone serves as a versatile heterocyclic building block in the synthesis of pharmaceutical compounds.

Application

1-Benzyl-4-piperidone is generally used as a building block in the synthesis of various medicinal compounds. Applications include the synthesis of:
  • Spirocyclic furopyridines as haloperidol-sensitive σ receptor ligands.
  • Multi-target-directed donepezil + propargylamine + 8-hydroxyquinoline (DPH) hybrids for the treatment of Alzheimer′s disease.
  • Spiropiperidine iminohydantoin aspartyl protease inhibitors.

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Piktogramy

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Warning

Kody zagrożeń

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Klasa składowania

10 - Combustible liquids

Temperatura zapłonu (°F)

159.8 °F

Temperatura zapłonu (°C)

71 °C

PPE (środki ochrony indywidualnej)

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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