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901950

Sigma-Aldrich

Alginate-RGD bioink

suitable for 3D bioprinting applications

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About This Item

Kod UNSPSC:
12352201
NACRES:
NA.23
Informacje o cenach i dostępności nie są obecnie dostępne.

Formularz

viscous liquid

zanieczyszczenia

<25 EU/mL Endotoxin

kolor

white

pH

6.5-7

gęstość

1.050 g/mL

Zastosowanie

3D bioprinting

temp. przechowywania

2-8°C

Opis ogólny

3D bioprinting is the printing of biocompatible materials, cells, growth factors, and the other supporting materials necessary to yield functional complex living tissues. 3D bioprinting has been used to generate several different types of tissue such as skin, bone, vascular grafts, and cartilage structures. Based upon the desired properties, different materials and formulations can be used to generate both hard and soft tissues. While several 3D printing methods exist, due to the sensitivity of the materials used, extrusion-based methods with bioinks are most commonly employed.

Material comes prepackaged in syringe with 5ml of product.
Alginate-RGD bioink, a natural biopolymer, is a biocompatible polysaccharide extracted from brown algae and modified with RGD peptide sequence by binding with peptide carboxylic acid functional group through carbodiimide chemistry.[1]

Zastosowanie

Alginate-RGD bioink has mild gelling characteristics at room temperature that makes it useful in the encapsulation of cells. It can be used in the formation of hydrogel-based bioink for the production of tissue-mimetic 3-D structures.[1][2][3]
Due to its low cost, biocompatibility, and facile gelation, alginate is one of the most common components of commercial bioinks. Alginate is a naturally-occurring polysaccharide, obtained from the cell walls of brown algae, that is composed of guluronic and mannuronic acid. Alginate has been shown to readily form hydrogels under mild conditions and Arg-Gly-Asp (RGD) motifs have been added to improve cell adhesion after printing. Alginate-RGD acellular bioink is provided as a ready-to-print, low endotoxin, and aseptic formulation in 5 mL syringes.

Informacje prawne

Product of Cellink
Ta strona może zawierać tekst przetłumaczony maszynowo.

Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number
MKCH0501

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Phage as versatile nanoink for printing 3-D cell-laden scaffolds
Lee D, et al.
Acta Biomaterialia, 29(15-16), 112-124 (2016)
3D bioprinting of hydrogel-based biomimetic microenvironments
Luo Y, et al.
Journal of Biomedical Materials Research. Part B, Applied Biomaterials, 107(5), 1695-1705 (2019)
Behavior of encapsulated MG-63 cells in RGD and gelatine-modified alginate hydrogels
Grigore A, et al.
Tissue Engineering: Part A, 20(15-16), 2140-2150 (2014)
Carmen C Piras et al.
Biomaterials science, 5(10), 1988-1992 (2017-08-23)
3D bioprinting is a new developing technology with lots of promise in tissue engineering and regenerative medicine. Being biocompatible, biodegradable, renewable and cost-effective, cellulosic nanomaterials have recently captured the attention of researchers due to their applicability as inks for 3D
P Selcan Gungor-Ozkerim et al.
Biomaterials science, 6(5), 915-946 (2018-03-02)
Bioprinting is an emerging technology with various applications in making functional tissue constructs to replace injured or diseased tissues. It is a relatively new approach that provides high reproducibility and precise control over the fabricated constructs in an automated manner

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Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Trójwymiarowy biodruk do modelowania tkanek i chorób

Profesor Shrike Zhang (Harvard Medical School, USA) omawia postępy w biodruku 3D modeli tkankowych do testowania leków in vitro, dokonuje przeglądu wyboru biokomponentów i przedstawia przykłady zastosowań biodruku 3D w biofabrykacji modeli tkankowych.

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