752940

(Trimethylphosphoranylidene)acetonitrile solution

0.5 M in THF

• Synonim(y): CMMP, Cyanomethylenetrimethylphosphorane solution
• Wzór empiryczny (zapis Hilla): C₅H₁₀NP
• Numer CAS: 176325-83-0
• Masa cząsteczkowa: 115.11
• NACRES: NA.22
• PubChem Substance ID: 329766326
• UNSPSC Code: 12352000
• MDL number: MFCD17013403
• Form: liquid

Właściwości

• form: liquid
• Quality Segment: 100
• concentration: 0.5 M in THF
• density: 0.896 g/mL at 25 °C
• functional group: nitrile, phosphine
• storage temp.: 2-8°C
• SMILES string: CP(C)(C)=CC#N
• InChI: 1S/C5H10NP/c1-7(2,3)5-4-6/h5H,1-3H3
• InChI key: KJFJIEHJCVSAKJ-UHFFFAOYSA-N

Opis

General description

(Trimethylphosphoranylidene)acetonitrile is a reagent generally employed in the Wittig olefination of less reactive carboxylic acid compounds like esters, N-Boc lactams, lactones, and imides to give α,β-unsaturated nitriles. It is also used as an alternate reagent for Mitsonobu reaction by replacing DEAD/PPh₃ for the alkylation of C-H and N-H bonds.

Other Notes

If precipitate is observed, warm gently to resolubilize

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS08,GHS05,GHS07
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H225,H302,H318,H335,H336,H351
• Ostrzeżenia: P202 - P210 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
• Narządy docelowe: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Klasa składowania: 3 - Flammable liquids
• Temperatura zapłonu (°F): -5.8 °F - closed cup
• Temperatura zapłonu (°C): -21.0 °C - closed cup