670359

Acetylthiomethyl-diphenylphosphine borane complex

≥98.0%

• Synonim(y): (T-4)-[S-[(Diphenylphosphino-κP)methyl] ethanethioate]trihydroboron
• Wzór empiryczny (zapis Hilla): C₁₅H₁₈BOPS
• Numer CAS: 446822-71-5
• Masa cząsteczkowa: 288.15
• UNSPSC Code: 12352200
• PubChem Substance ID: 329760266
• NACRES: NA.22

Właściwości

• assay: ≥98.0%
• form: solid
• reaction suitability: reaction type: click chemistry, reagent type: ligand; reaction type: Staudinger Reaction
• mp: 52-55 °C
• functional group: phosphine
• storage temp.: 2-8°C
• SMILES string: B.CC(=O)SCP(c1ccccc1)c2ccccc2
• InChI: 1S/C15H15OPS.BH3/c1-13(16)18-12-17(14-8-4-2-5-9-14)15-10-6-3-7-11-15;/h2-11H,12H2,1H3;1H3
• InChI key: MXPNVFCCEGQGEN-UHFFFAOYSA-N

Opis

Application

• Traceless Staudinger ligation reagent with borane protecting group.
• The borane group stabilizes the phosphine against oxidation and can be easily removed with mild basic or acidic conditions to yield the active phosphine.
• After reaction with an azide, the phosphine is eliminated in the presence of water to yield a native amide bond.
• Used in the synthesis of cyclic peptides.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Sold under license for research and development purposes only. US Patent 6,974,884 and related patents apply

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H315,H319,H335
• Ostrzeżenia: P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Narządy docelowe: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Gloves