57917
SUPELCOSIL™ ABZ+Plus (3 µm) HPLC Columns
L × I.D. 10 cm × 2.1 mm, HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
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product name
SUPELCOSIL™ ABZ+Plus HPLC Column, 3 μm particle size, L × I.D. 10 cm × 2.1 mm
Agency
suitable for USP L60
feature
endcapped
manufacturer/tradename
SUPELCOSIL™
extent of labeling
12.0% carbon loading
parameter
≤70 °C temp. range
400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
10 cm × 2.1 mm
surface area
170 m2/g
surface coverage
surface coverage 3.4 μmol/m2
matrix
silica gel, spherical particle platform
matrix active group
amide, alkyl phase
particle size
3 μm
pore size
120 Å
pH range
2-7.5
application(s)
food and beverages
separation technique
reversed phase
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General description
SUPELCOSIL ABZ+Plus columns offer both high deactivation and unique selectivity. Deactivated silica particles of very narrow particle size distribution ensure high efficiency with low back pressure. After bonding and endcapping reactions, the ABZ+Plus phase effectively shields unreacted silanol groups on the silica, preventing them from interacting with most analytes, and provides symmetric peaks regardless of an analyte′s functionality. The phase also allows you to use low ionic strength buffers without having to add an ion-suppressing modifier. ABZ+Plus enables you to use simple mobile phases when analyzing the most difficult compounds; acids, strongly basic compounds, and zwitterions.
suitable for L60 per USP
suitable for L60 per USP
Features and Benefits
• High efficiency for polar, nonpolar, and charged analytes
• Symmetric peaks for the most reactive compounds
• Unique selectivity for polar and charged compounds
• Symmetric peaks for the most reactive compounds
• Unique selectivity for polar and charged compounds
Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
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Zhongping John Lin et al.
Journal of pharmaceutical and biomedical analysis, 37(4), 757-762 (2005-03-31)
A highly sensitive method was developed and validated for determining the free fraction of flunarizine in human plasma. Equilibrium dialysis was used for the separation of free (unbound) drug and liquid chromatography/tandem mass spectrometry (LC-MS/MS) was used for quantitation. Post-dialysis
Tânia M G Almeida et al.
Chemistry & biodiversity, 2(12), 1691-1700 (2006-12-29)
Absorption, distribution, metabolism, and excretion (ADME) properties are of invaluable importance to a bioactive compound. Permeation process is one of the most widely studied by many different techniques. Among them, reversed-phase liquid chromatography (RP-LC) is proving to be of great
K Ary et al.
Journal of chromatography. A, 797(1-2), 221-226 (1998-05-16)
A reversed-phase high-performance liquid chromatographic method with electrochemical detection has been developed for the determination of buspirone from human plasma. The separation was carried out by using a Supelcosil ABZ+ plus C18 reversed-phase column and 0.05 M potassium dihydrogenphosphate (pH
W Pan et al.
Journal of chromatography. B, Biomedical sciences and applications, 703(1-2), 129-138 (1998-02-03)
A sensitive, specific and precise HPLC-UV assay was developed to quantitate cocaine (COC) and its metabolites benzoylecgonine (BE), norcocaine (NC) and cocaethylene (CE) in rat plasma. After adding 50 microl of the internal standard solution (bupivacaine, 8 microg/ml) and 500
A B Baranda et al.
Talanta, 67(5), 933-941 (2008-10-31)
A liquid-liquid extraction method using diethyl ether as organic solvent was optimized simultaneously for five 1,4-dihydropyridines (amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine) belonging to the group of calcium channel blockers. Some experimental tools such as a full factorial design, a
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