SRP0440
UBE1 active human
recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
Synonym(s):
UBA1, UBA1A, ubiquitin-like modifier activating enzyme 1
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
Assay
≥80% (SDS-PAGE)
form
aqueous solution
mol wt
118 kDa
packaging
pkg of 100 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... UBA1(7317)
General description
Human UBE1 (GenBank Accession No. NM_003334) amino-acids 2-end with N-terminal FLAG-tag, MW=118 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Application
Useful in conjunction with E2 and E3 for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Yu-Hui Li et al.
Experimental cell research, 371(1), 250-254 (2018-08-18)
Ninety percent of all cancer related deaths happen due to metastatic progression. One important protein facilitating metastatic progression in hepatocellular carcinoma (HCC) is the metastasis associated 1 protein (MTA-1). We have earlier shown that in the context of HCC and
Juliane Ramser et al.
American journal of human genetics, 82(1), 188-193 (2008-01-09)
X-linked infantile spinal muscular atrophy (XL-SMA) is an X-linked disorder presenting with the clinical features hypotonia, areflexia, and multiple congenital contractures (arthrogryposis) associated with loss of anterior horn cells and infantile death. To identify the XL-SMA disease gene, we performed
Yi Liu et al.
Journal of experimental botany, 71(18), 5562-5576 (2020-05-27)
Plants can be simultaneously exposed to multiple stresses. The interplay of abiotic and biotic stresses may result in synergistic or antagonistic effects on plant development and health. Temporary drought stress can stimulate plant immunity; however, the molecular mechanism of drought-induced
UBE1 expression in extranodal NK/T cell lymphoma, nasal type.
Z L Su et al.
Leukemia & lymphoma, 49(9), 1821-1822 (2008-07-29)
J Romaní-Aumedes et al.
Cell death & disease, 5, e1364-e1364 (2014-08-08)
Mutations in the PARK2 gene are associated with an autosomal recessive form of juvenile parkinsonism (AR-JP). These mutations affect parkin solubility and impair its E3 ligase activity, leading to a toxic accumulation of proteins within susceptible neurons that results in
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