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SML3255

Sigma-Aldrich

Crocetin

≥98% (HPLC)

Synonym(s):

α-Crocetin, 2,6,11,15-tetramethyl-2E,4E,6E,8E,10E,12E,14E-hexadecaheptaenedioic acid, NSC 407300, Trans-crocetin, Transcrocetin

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5 MG
PLN 36.60
25 MG
PLN 228.00

PLN 36.60

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5 MG
PLN 36.60
25 MG
PLN 228.00

About This Item

Empirical Formula (Hill Notation):
C20H24O4
CAS Number:
27876-94-4
Molecular Weight:
328.40
MDL number:
MFCD00017359
UNSPSC Code:
12352200
NACRES:
NA.77

PLN 36.60

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

faint brown to dark brown
deep red-brown

solubility

DMSO: 2 mg/mL, clear

storage temp.

−70°C

SMILES string

OC(=O)\C(=C\C=C\C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C(=O)O)\C)\C

InChI

1S/C20H24O4/c1-15(11-7-13-17(3)19(21)22)9-5-6-10-16(2)12-8-14-18(4)20(23)24/h5-14H,1-4H3,(H,21,22)(H,23,24)/b6-5+,11-7+,12-8+,15-9+,16-10+,17-13+,18-14+

InChI key

PANKHBYNKQNAHN-MQQNZMFNSA-N

Biochem/physiol Actions

Apocarotenoid dicarboxylic acid shown to exhibit antioxidant, antiproliferative, anti-inflammatory, cardioprotective, and antinociceptive activity.
Crocetin is a natural apocarotenoid dicarboxylic acid, found naturally in saffron crocus and gardenia flowers, that has been shown to exhibit antioxidant, antiproliferative, anti-inflammatory, cardioprotective, neuroprotective, and antinociceptive activity.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000419819
0000419821
0000419821
0000419819
0000327978

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Eiji Inoue et al.
Journal of natural medicines, 72(1), 274-279 (2017-11-18)
Saffron, the stigma of Crocus sativus Linné (Iridaceae family), has been known to inhibit aggregation of β-amyloid, a nerve tissue protein. α-Synuclein (αS) is a 140-amino acid protein found abundantly in various regions of the brain. Its abnormal aggregation and
Kyriaki Hatziagapiou et al.
Current neuropharmacology, 17(4), 377-402 (2018-03-23)
Reactive oxygen species and reactive nitrogen species, which are collectively called reactive oxygen-nitrogen species, are the inevitable by-products of cellular metabolic redox reactions, such as oxidative phosphorylation in the mitochondrial respiratory chain, phagocytosis, reactions of biotransformation of exogenous and endogenous
Maliheh Moradzadeh et al.
Journal of cellular physiology, 233(3), 2170-2182 (2017-04-14)
Natural products have gained a wide popularity as chemopreventive and anti-cancer agents owing to their multi-mechanistic mode of action, availability and synergism with several conventional chemotherapeutic agents. Crocetin is a carotenoid compound isolated from the stigma of Crocus sativus L.

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