SAB4501145

Anti-LATS1 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Kinase phosphorylated during mitosis protein, Large tumor suppressor homolog 1, Serine/threonine-protein kinase kpm, WARTS protein kinase, h-warts/ Large tumor suppressor homolog 2
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 126 kDa
• species reactivity: human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:40000; immunohistochemistry: 1:50-1:100
• NCBI accession no.: O95835
• UniProt accession no.: O95835
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... LATS1(9113)

Description

General description

Anti-LATS1 Antibody detects endogenous levels of total LATS1 protein.

The LATS1 (large tumor suppressor kinase 1) gene encodes a serine/threonine kinase and is located on human chromosome 6q24-25. It is present in the mitotic apparatus. It is also called as WARTS.

Immunogen

The antiserum was produced against synthesized peptide derived from human LATS1/2.

Immunogen Range: 1041-1090

Biochem/physiol Actions

The LATS1 (large tumor suppressor kinase 1) protein repress the multiplication and invasion of cervical cancer. It acts as a cell cycle inhibitor. Low level expression of LATS1 is associated with the progression and prognosis of glioma. It is a tumor suppressor gene, thereby it participates in various mitotic processes.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable