P6972

Monoclonal Anti-Interferon-γ−R-Phycoerythrin antibody produced in mouse

clone 25723, purified immunoglobulin, saline solution

• Synonym(s): Monoclonal Anti-Interferon-γ
• NACRES: NA.41
• UNSPSC Code: 51111800
• Conjugate: phycoerythrin (R-PE) conjugate
• Clone: 25723, monoclonal
• Application: FACS
• Citations: 1

Properties

• biological source: mouse
• Quality Level: 200
• conjugate: phycoerythrin (R-PE) conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 25723, monoclonal
• form: saline solution
• species reactivity: human
• technique(s): flow cytometry: suitable
• isotype: IgG2b
• UniProt accession no.: P01579
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: human ... IFNG(3458)

Description

General description

Human Interferon-γ (IFN-γ) is a Type I cytokine produced by the lymphocytes activated in response to specific antigens or mitogens. It has a pivotal role in activating primed macrophages for nonspecific tumoricidal activity as well as can stimulate monocytes for enhanced cytotoxicity against tumor cells. It also has several biological functions like inhibition of cell or tumor growth, promotion of B cell differentiation into plasma cells and antiviral activity. Further, it can enhance the cytotoxicity of natural killer cells and T-cells. Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody reacts specifically with human IFN-γ.

Immunogen

recombinant human IFN-γ

Application

Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody can be used in flow cytometry for detecting intracytoplasmic cytokines and enumerating cytokine-producing cells in a mixed population.

Biochem/physiol Actions

The conjugates will identify and quantitate cells containing intracellular forms of human IFN-γ by flow cytometry.

Physical form

Solution in saline containing up to 0.5% bovine serum albumin and 0.1% sodium azide as a preservative.

Preparation Note

Purified antibody is conjugated to R-phycoerythrin (PE).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves