M7782
Antiflammin-1
≥97% (HPLC)
Synonym(s):
Anti-inflammatory peptide 1, Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser
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About This Item
Assay
≥97% (HPLC)
composition
Peptide content, ~70%
storage temp.
−20°C
SMILES string
CSCCC(N)C(=O)NC(CCC(N)=O)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(CO)C(O)=O
Biochem/physiol Actions
Inhibits synthesis of platelet activating factor.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Antiflammins inhibit synthesis of platelet-activating factor and intradermal inflammatory reactions.
Advances in experimental medicine and biology, 279, 161-172 (1990-01-01)
Inhibition of phospholipase A2 by uteroglobin and antiflammin peptides.
Advances in experimental medicine and biology, 279, 137-160 (1990-01-01)
Biochemistry, 48(46), 11142-11148 (2009-10-21)
Electrophilic halogenating agents, including hypohalous acids and haloamines, oxidize free methionine and the N-terminal methionines of peptides and proteins (e.g., Met-1 of anti-inflammatory peptide 1 and ubiquitin) to produce dehydromethionine (a five-membered isothiazolidinium heterocycle). Amide derivatives of methionine are oxidized
Toxicon : official journal of the International Society on Toxinology, 40(1), 9-21 (2001-10-17)
The mode of action of venom from the ectoparasitic wasp Nasonia vitripennis in eliciting cell death was examined using an in vitro approach with BTI-TN-5B1-4 cells, and the cell responses were compared to those evoked by the extensively studied wasp
Experimental dermatology, 6(4), 181-185 (1997-08-01)
The potential of an anti-inflammatory peptide (antiflammin 1) to reduce irritation when delivered transdermally by iontophoresis was examined. A model drug irritant, chlorpromazine, was co-delivered with and without antiflammin 1 by iontophoresis to hairless guinea pigs transdermally. Quantitative skin irritation
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