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Key Documents

M5064

Sigma-Aldrich

Rp-2′-O-Monobutyryladenosine 3′,5′-cyclic monophosphorothioate

≥97% (HPLC), solid

Synonym(s):

Rp-2′-O-MB-cAMPS

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About This Item

CAS Number:
UNSPSC Code:
41106305
PubChem Substance ID:

Assay

≥97% (HPLC)

form

solid

mol wt

apparent mol wt 437.3 Da

packaging

vial of 5 μmol (approx. 2 mg)

storage temp.

−20°C

SMILES string

CCCC(=O)O[C@@H]1[C@@H]2OP(O)(=S)OC[C@H]2O[C@H]1n3cnc4c(N)ncnc34

InChI

1S/C14H18N5O6PS/c1-2-3-8(20)24-11-10-7(4-22-26(21,27)25-10)23-14(11)19-6-18-9-12(15)16-5-17-13(9)19/h5-7,10-11,14H,2-4H2,1H3,(H,21,27)(H2,15,16,17)/t7-,10-,11-,14-,26?/m1/s1

InChI key

XSAXBAAZBXKFFH-IDYJAONBSA-N

Application

Eliminates first messenger-stimulated phosphorylation by cyclic AMP-dependent protein kinase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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U M Vischer et al.
Blood, 91(1), 118-127 (1998-02-07)
von Willebrand factor (vWF) is stored and released from endothelial secretory granules called Weibel-Palade (WP) bodies. Acute release can be induced by thrombin, histamine, and other mediators of thrombosis or inflammation. Their effect is thought to be mediated by an

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