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J4137

JS-K

≥97%, Nitric oxide donor

Synonym(s):

O2-(2,4-Dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
PLN 663.00
25 mg
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PLN 2,100.00

About This Item

Empirical Formula (Hill Notation):
C13H16N6O8
CAS Number:
Molecular Weight:
384.30
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥97%
Storage condition:
desiccated

PLN 663.00


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Product Name

JS-K, ≥97%

Quality Segment

assay

≥97%

storage condition

desiccated

solubility

DMSO: soluble 9.3 mg/mL, H2O: insoluble

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCOC(=O)N1CCN(CC1)\[N+]([O-])=N\Oc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O

InChI

1S/C13H16N6O8/c1-2-26-13(20)15-5-7-16(8-6-15)19(25)14-27-12-4-3-10(17(21)22)9-11(12)18(23)24/h3-4,9H,2,5-8H2,1H3/b19-14-

InChI key

DNJRNBYZLPKSHV-RGEXLXHISA-N

Biochem/physiol Actions

JS-K belongs to the class of diazeniumdiolate prodrug. It generates nitric oxide when metabolized by glutathione S-transferases (GST), which ensures optimal activity of JS-K. It has tumor growth inhibition action in human prostate cancer and leukemia.
Nitric oxide donor; antiproliferative.

Legal Information

Covered by US Patent No 6,610,660

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This Item
SML0522SML2256SML1405
assay

≥97%

assay

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

desiccated

solubility

DMSO: soluble 9.3 mg/mL, H2O: insoluble

solubility

DMSO: 2 mg/mL (clear solution, warmed)

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

wet ice


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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