I0157

Ibudilast

≥99% (HPLC), Phosphodiesterase IV inhibitor, solid

• Synonym(s): 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl] 1-propanone, 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine, KC-404
• Empirical Formula (Hill Notation): C₁₄ H₁₈ N₂ O
• CAS Number: 50847-11-5
• Molecular Weight: 230.31
• UNSPSC Code: 41106305
• PubChem Substance ID: 24278482
• NACRES: NA.77
• MDL number: MFCD00864808
• Assay: ≥99% (HPLC)
• Form: solid

Properties

• Product Name: Ibudilast, ≥99% (HPLC), solid
• Quality Segment: 200
• assay: ≥99% (HPLC)
• form: solid
• color: white
• solubility: DMSO: soluble 28 mg/mL, H₂O: soluble 4.5 mg/mL
• storage temp.: 2-8°C
• SMILES string: CC(C)C(=O)c1c(nn2ccccc12)C(C)C
• InChI: 1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3
• InChI key: ZJVFLBOZORBYFE-UHFFFAOYSA-N
• Gene Information: human ... PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144)

Description

Biochem/physiol Actions

Phosphodiesterase IV (PDE4) inhbitor. Inhibits platelet aggregation. Anti-asthma drug.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves