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Cytochrome P450 2C9*2 (R144C), human

Name: Cytochrome P450 2C9*2 (R144C), human
Brand: SIGMA

recombinant, expressed in E. coli

Synonym(s):

Cytochrome P450, purified, soluble, CYP2C9 Arg144Cys, CYP2C9 R144C

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About This Item

CAS Number:

9035-51-2

NACRES:

NA.54

UNSPSC Code:

12352204

Form:

liquid

Biological source:

human

Recombinant:

expressed in E. coli

Mol wt:

54370 g/mol

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Properties

biological source

human

Quality Segment

200

recombinant

expressed in E. coli

description

purified, soluble

form

liquid

specific activity

12-88 units/mg protein

mol wt

54370 g/mol

concentration

3.5-25 mg protein/mL (protein), 50-150 nmol/mL (P450), 6-14 ng/mg protein (specific content)

NCBI accession no.

NP_000762.2

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... CYP2C9(1559)

Description

General description

Supplied as purified soluble proteins, rather than microsomal preparations.

Other Notes

One unit will convert 1.0 nanomole of diclofenac (2-(2,6-dichloranilino) phenylacetic acid) 4`-hydroxylated product per minute at pH 7.4 at 37 °C.

Visit our drug metabolism resources: www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/xenobiotics.html

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This Item	H4542	H5042	MTOXCE2D6
Sigma-Aldrich H4667 Cytochrome P450 2C9*2 (R144C), human	Sigma-Aldrich H4542 Cytochrome P450 2C9*3 (I359L), human	Sigma-Aldrich H5042 Cytochrome P450 3A4 human	Sigma-Aldrich MTOXCE2D6 CypExpress^™ 2D6 Cytochrome P450 human
recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in Pichia pastoris
biological source human	biological source human	biological source human	biological source human
concentration 3.5-25 mg protein/mL (protein), 6-14 ng/mg protein (specific content), 50-150 nmol/mL (P450)	concentration 3.5-25 mg protein/mL (protein), 50-150 nmol/mL, 6-14 nmol/mg protein (specific content)	concentration 3.5-25 mg protein/mL (protein), 50-150 nmol/mL (P450), 6-14 nmol/mg protein (specific content)	concentration -
form liquid	form liquid	form liquid	form dry powder
mol wt 54370 g/mol	mol wt 54423.1 g/mol	mol wt 57318.7 g/mol	mol wt -
storage temp. −70°C	storage temp. −70°C	storage temp. −70°C	storage temp. −70°C

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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