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H4128

Sigma-Aldrich

11β-Hydroxytestosterone

crystalline

Synonym(s):

11β,17β-Dihydroxyandrost-4-en-3-one, 4-Androstene-11β,17β-diol-3-one

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About This Item

Empirical Formula (Hill Notation):
C19H28O3
CAS Number:
1816-85-9
Molecular Weight:
304.42
MDL number:
MFCD00010481
UNSPSC Code:
12352200
PubChem Substance ID:
24895621

form

crystalline

drug control

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

color

light yellow

SMILES string

CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2O

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Biochem/physiol Actions

Structure-activity relationships of 11-substituted testosterone derivatives as progesterone agonists, and their effect on growth and differentiation of human decidual cells.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H351,H360

Precautionary Statements

P201 - P281 - P308 + P313

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
056F4070

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P M Rosenblum et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 82(4), 659-665 (1985-01-01)
Highly specific antisera for 11-keto- and 11 beta-hydroxytestosterone have been raised in sheep. Assay systems for the simultaneous measurement of 11-ketotestosterone, 11 beta-hydroxytestosterone, testosterone, progesterone and estradiol-17 beta were validated for Ictalurus nebulosus plasma and Carassius auratus serum. In males
T Leitz et al.
General and comparative endocrinology, 58(3), 471-477 (1985-06-01)
Minced testes of the Siamese fighting fish Betta splendens were incubated with [14C]androstenedione at 27 degrees C for 15, 30, 60, and 120 min. The metabolic products were characterized by paper and thin-layer chromatography, derivative formation, and eventually by crystallization
S T Lee et al.
General and comparative endocrinology, 99(1), 41-49 (1995-07-01)
The steroidogenic potential of gonadal tissues of the protogynous grouper (Epinephelus tauvina) was examined before and after sex inversion with 17 alpha-methyltestosterone. Incubations of gonadal tissues of the fish with [3H]testosterone resulted in the biosynthesis of 5 beta-androstane-3 beta, 17
F Ollevier et al.
General and comparative endocrinology, 61(2), 214-228 (1986-02-01)
The O-pentafluorobenzyloxime (OPFB)-heptafluorobutyrylester (HFB) derivatives of hemolymph steroid extracts from both male and female Astacus leptodactylus were subjected to negative ion chemical ionization and capillary gas chromatography-mass spectrometry (NCI/GC-MS). Five nonecdysteroid steroids, namely pregnenolone, 17 alpha-hydroxypregnenolone, testosterone, cholesterol, and 6
R Schulz
General and comparative endocrinology, 64(2), 312-319 (1986-11-01)
Male rainbow trout show high plasma androgen levels beginning with the period of full spermatogenesis until the end of spermiation. The difficulties in explaining the steroid levels in regard to the concomitant changes of the plasma GTH concentrations prompted investigations
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