G1876
L-Glutamic acid γ-ethyl ester
Synonym(s):
L-Glutamic acid 5-ethyl ester
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About This Item
Linear Formula:
C2H5OCOCH2CH2CH(NH2)COOH
CAS Number:
Molecular Weight:
175.18
Beilstein:
1725589
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
application(s)
peptide synthesis
storage temp.
−20°C
SMILES string
CCOC(=O)CC[C@H](N)C(O)=O
InChI
1S/C7H13NO4/c1-2-12-6(9)4-3-5(8)7(10)11/h5H,2-4,8H2,1H3,(H,10,11)/t5-/m0/s1
InChI key
XMQUEQJCYRFIQS-YFKPBYRVSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Rebecca J Chapman et al.
The European journal of neuroscience, 26(8), 2257-2268 (2007-09-27)
We have explored the potential involvement of the three main classes of metabotropic glutamate receptor in the modulation of a spinal locomotor network using tadpoles of the anuran amphibian Xenopus laevis. Selective activation of group I receptors in Xenopus embryos
H Thompson et al.
Neuropharmacology, 47(6), 822-832 (2004-11-06)
Previous work from this laboratory indicates that Group II/III metabotropic glutamate (mGlu) receptors modulate responses of SC neurones to visual stimuli in vivo. It is thought that tonic levels of glutamate may be sufficient to activate some mGlu receptors. We
D Manahan-Vaughan
Neuropharmacology, 37(12), 1459-1464 (1999-01-14)
Activation of group 1 metabotropic glutamate receptors (mGluRs) has been shown to facilitate the induction of tetanically evoked long-term potentiation in vivo, whereas group 2 mGluR antagonists inhibit long-term depression (LTD) in the CA1 region. LTD has not been successfully
Cristina Marchetti et al.
Experimental brain research, 164(3), 406-410 (2005-07-02)
This study examined whether activation of group I metabotropic glutamate receptors (mGluRs) could modulate synaptic inhibition of spinal motoneurons in the neonatal rat isolated spinal cord. Recurrent inhibitory postsynaptic potentials (IPSPs) generated by Renshaw cells were evoked via antidromic stimulation
Vilen A Movsesyan et al.
Journal of neurotrauma, 23(2), 117-127 (2006-03-01)
The effects of group II mGluR activation by selective agonist (-)-2-oxa-4-aminobicyclo[3.1. 0]hexane-4,6-dicarboxylate (LY379268) were examined in a mouse model of controlled cortical impact (CCI)-induced brain injury and in primary neuronal/glial and neuronal cultures subjected to mechanical trauma. Systemic administration of
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