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Key Documents

D157406

Sigma-Aldrich

2-Dimethylaminoethanol

Synonym(s):

N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethylethanolamine, Jeffcat DMEA

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About This Item

Linear Formula:
(CH3)2NCH2CH2OH
CAS Number:
Molecular Weight:
89.14
Beilstein:
1209235
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

vapor pressure

100 mmHg ( 55 °C)
6.12 mmHg ( 20 °C)

Quality Level

refractive index

n20/D 1.4294 (lit.)

bp

134-136 °C (lit.)

mp

−70 °C (lit.)

density

0.886 g/mL at 20 °C (lit.)

SMILES string

CN(C)CCO

InChI

1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3

InChI key

UEEJHVSXFDXPFK-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

104.0 °F - Seta closed cup

Flash Point(C)

40 °C - Seta closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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K M Houston et al.
Parasitology, 135(Pt 1), 55-61 (2007-09-26)
Juvenile female Litomosoides sigmodontis secrete a protein (Juv-p120) highly modified with dimethylethanolamine (DMAE). In an attempt to establish the source of this decoration worms were pulsed with [3H]-choline and [3H]-ethanolamine and the radio-isotope labelled products analysed. Both isotope labels were
Ouassila Amiri-Attou et al.
Molecules (Basel, Switzerland), 10(3), 545-551 (2007-11-17)
We report herein the synthesis of substituted 2-(6-nitrobenzo[1,3]dioxol-5-yl)-1- aryl ethanols and 2-(6-nitrobenzo[1,3]dioxol-5-yl)-propionic acid ethyl esters from the reaction of 5-chloromethyl-6-nitrobenzo[1,3]dioxole with various aromatic carbonyl and alpha- carbonyl ester derivatives using the tetrakis(dimethylamino)ethylene (TDAE) methodology.
Zhifeng Fu et al.
Analytica chimica acta, 638(2), 220-224 (2009-03-31)
Numerous drugs are carboxylic acid derivatives containing amino group, and hydrolysis reaction of these agents often generates toxic amines. Thus, the detection of amine impurity is of great importance in drug quality control of these amino group-containing ester and amide.
Dominique Slaets et al.
European journal of nuclear medicine and molecular imaging, 37(11), 2136-2145 (2010-06-18)
[(18)F]Fluoromethylcholine ([(18)F]FCho) is a radiotracer generally used for tumour visualization in patients. Due to high levels of dimethylaminoethanol (DMAE) remaining in [(18)F]FCho solutions synthesized by currently available methods, tumour visualization might be compromised. An improved purification method involving an optimized
B Sommerfeld
Phytomedicine : international journal of phytotherapy and phytopharmacology, 14(11), 711-715 (2007-10-10)
Tricutan is a combination product of herbal extracts traditionally used for treatment of skin conditions, together with dimethylaminoethanol. The effectiveness of Tricutan in improving skin firmness and elasticity in photoaged facial skin was examined in a randomised, placebo-controlled, double-blind, split-face

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