B9936

Boc-Ile-Glu-Gly-Arg-7-amido-4-methylcoumarin acetate salt

Name: Boc-Ile-Glu-Gly-Arg-7-amido-4-methylcoumarin acetate salt
Brand: SIGMA

≥97% (HPLC), powder

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About This Item

Empirical Formula (Hill Notation):

C₃₄H₅₀N₈O₁₀

CAS Number:

65147-06-0

Molecular Weight:

730.81

MDL number:

MFCD00080223

UNSPSC Code:

12352204

NACRES:

NA.32

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Key Documents

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Product Name

Boc-Ile-Glu-Gly-Arg-7-amido-4-methylcoumarin acetate salt, ≥97% (HPLC)

SMILES string

N(C(CCCN=C(N)N)C(=O)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)OC(C)(C)C)C(CC)C)CCC(=O)O)c1cc2c(cc1)C(=CC(=O)O2)C

InChI

1S/C34H50N8O10/c1-7-18(2)28(42-33(50)52-34(4,5)6)31(49)40-23(12-13-26(44)45)29(47)38-17-25(43)41-30(48)22(9-8-14-37-32(35)36)39-20-10-11-21-19(3)15-27(46)51-24(21)16-20/h10-11,15-16,18,22-23,28,39H,7-9,12-14,17H2,1-6H3,(H,38,47)(H,40,49)(H,42,50)(H,44,45)(H4,35,36,37)(H,41,43,48)

InChI key

PWOIMWXLMWHALO-UHFFFAOYSA-N

assay

≥97% (HPLC)

form

powder

solubility

methanol: 2 mg/mL, clear, colorless

storage temp.

−20°C

Quality Level

200

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Show Differences

1 of 4

This Item	B4636	S9761	P9273
Sigma-Aldrich B9936 Boc-Ile-Glu-Gly-Arg-7-amido-4-methylcoumarin acetate salt	Sigma-Aldrich B4636 Boc-Leu-Ser-Thr-Arg-7-amido-4-methylcoumarin	Sigma-Aldrich S9761 N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin	Sigma-Aldrich P9273 Pro-Phe-Arg-7-amido-4-methylcoumarin
assay ≥97% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥95%
solubility methanol: 2 mg/mL, clear, colorless	solubility ethanol: 2 mg/mL, clear, colorless	solubility methanol: 50 mg/mL, clear, colorless	solubility methanol: 50 mg/mL, clear, colorless to faintly yellow
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

General description

A sensitive and specific fluorogenic substrate for factor Xa.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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The use of fluorogenic peptide substrates for the detection of coagulation factors II and X after electrophoresis.

P G Board

Annals of human genetics, 46(Pt 4), 293-298 (1982-10-01)

New fluorogenic substrates for alpha-thrombin, factor Xa, kallikreins, and urokinase.

T Morita et al.

Journal of biochemistry, 82(5), 1495-1498 (1977-11-01)

Twenty peptide-4-methylcoumarin amides (MCA) were newly synthesized and tested as possible substrates for alpha-thrombin, factor Xa, kallikreins, urokinase, and plasmin. These fluorogenic peptides contained arginine-MCA as the carboxyl-terminus. Release of 7-amino-4-methylcoumarin was determined fluorometrically. Of these peptides, the following were

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