B950-05
Bovine Renal Artery Smooth Muscle Cells: BRASMC (Cryovial)
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About This Item
NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
bovine renal artery (normal, tunica intima and media)
Growth mode:
Adherent
Morphology:
smooth muscle
Relevant disease(s):
renal disease; cardiovascular diseases
biological source
bovine renal artery (normal, tunica intima and media)
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
2n = 60
morphology
smooth muscle
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
renal disease; cardiovascular diseases
shipped in
dry ice
storage temp.
−196°C
Quality Level
Preparation Note
- 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 12 doublings
Please refer to the BRASMC Culture Protocol.
Application
blood flow to kidneys
Biochem/physiol Actions
Artery
General description
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Bovine Renal Artery Smooth Muscle Cells (BRASMC) are derived from tunica intima and tunica media of normal bovine renal arteries. They are cryopreserved at second passage and can be cultured and propagated at least 12 population doublings. Studies show cyclosporine-induced renal artery smooth muscle contraction is associated with increases in the phosphorylation of specific contractile regulatory proteins1. The renal artery smooth muscle is uniquely refractory to angiotensin stimulation and may be protective in the role of the kidney in regulating blood pressure through the renin-angiotensin system2.
Beall, A. et al, Biochem Biophys Acta., 1449(1):41-9 (1999)
Whitney, E.G. et al, J. Surg. Res. 61(2):307-10 (1996)
Products are for research use only. They are not intended for human, animal, or diagnostic application.
Animal tissues were USDA inspected.
Bovine Renal Artery Smooth Muscle Cells (BRASMC) are derived from tunica intima and tunica media of normal bovine renal arteries. They are cryopreserved at second passage and can be cultured and propagated at least 12 population doublings. Studies show cyclosporine-induced renal artery smooth muscle contraction is associated with increases in the phosphorylation of specific contractile regulatory proteins1. The renal artery smooth muscle is uniquely refractory to angiotensin stimulation and may be protective in the role of the kidney in regulating blood pressure through the renin-angiotensin system2.
Beall, A. et al, Biochem Biophys Acta., 1449(1):41-9 (1999)
Whitney, E.G. et al, J. Surg. Res. 61(2):307-10 (1996)
Products are for research use only. They are not intended for human, animal, or diagnostic application.
Animal tissues were USDA inspected.
Other Notes
Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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