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A0788

3-Aminobenzamide

≥99% (TLC), PARP inhibitor, powder

Synonym(s):

3-AB, 3-ABA

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100 mg
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PLN 362.00
PLN 307.70
250 mg
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PLN 590.00
PLN 501.50
1 g
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PLN 1,420.00
PLN 1,207.00
5 g
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PLN 7,420.00

About This Item

Linear Formula:
H2NC6H4CONH2
CAS Number:
3544-24-9
Molecular Weight:
136.15
NACRES:
NA.77
PubChem Substance ID:
24278206
UNSPSC Code:
12352200
EC Number:
222-586-9
MDL number:
MFCD00007989
Assay:
≥99% (TLC)
Form:
powder

PLN 307.70

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Product Name

3-Aminobenzamide, ≥99% (TLC)

Quality Segment

200

assay

≥99% (TLC)

form

powder

color

white to off-white

mp

115-116 °C (lit.)

solubility

ethanol: 50 mg/mL, clear, light yellow, DMSO: soluble, H2O: soluble (may require gentle heating)

storage temp.

room temp

SMILES string

NC(=O)c1cccc(N)c1

InChI

1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)

InChI key

GSCPDZHWVNUUFI-UHFFFAOYSA-N

Gene Information

mouse ... Parp1(11545)

Application

3-Aminobenzamide has been used as a poly-(ADP-ribose) polymerase (PARP) inhibitor in various experimental studies.

Biochem/physiol Actions

3-Aminobenzamide enhances cell death, unscheduled DNA synthesis and repair replication by interrupting the rejoining of DNA strand breaks induced by both ionizing radiations and several alkylating agents. It has an ability to inhibit the activity of nuclear enzyme poly (ADP-ribose) synthetase (PARS). 3-Aminobenzamide exhibits protective action against myocardial reperfusion injury and local inflammation.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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Show Differences

1 of 1

This Item
A9657F0429M1404
3-Aminobenzamide ≥99% (TLC)

Sigma-Aldrich

A0788

3-Aminobenzamide

DL-Aminoglutethimide

Sigma-Aldrich

A9657

DL-Aminoglutethimide

Flunixin meglumine ≥98% (HPLC)

Sigma-Aldrich

F0429

Flunixin meglumine

Nocodazole ≥99% (TLC), powder

Sigma-Aldrich

M1404

Nocodazole

assay

≥99% (TLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

≥99% (TLC)

form

powder

form

powder or crystals

form

powder

form

powder

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

300

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

2-8°C

solubility

ethanol: 50 mg/mL, clear, light yellow, H2O: soluble (may require gentle heating), DMSO: soluble

solubility

H2O: slightly soluble 0.2 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.2 mg/mL, 0.1 M HCl: soluble, acetonitrile: soluble, methanol: soluble

solubility

H2O: freely soluble

solubility

DMSO: soluble 10 mg/mL (may require heating), H2O: insoluble

color

white to off-white

color

white

color

white to beige

color

-

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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