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31395

Dextran sulfate sodium salt from Leuconostoc spp.

Mr ~500,000

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10 G

PLN 347.00

50 G

PLN 1,140.00

PLN 347.00

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About This Item

CAS Number:
9011-18-1
UNSPSC Code:
12352201
NACRES:
NA.21
MDL number:
MFCD00081551

Key Documents

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biological source

(Leuconostoc spp.)

form

powder

mol wt

Mr ~500,000

composition

Sulfur Content, 16.0-19.0% (dry basis)

manufacturer/tradename

EDQM

useful pH range

6.0-8.0 (10 g/L)

solubility

H2O: freely soluble 50 mg/mL, clear

anion traces

chloride (Cl-): ≤100 mg/kg

cation traces

Ca: ≤200 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤1000 mg/kg, Mg: ≤100 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

storage temp.

room temp

Quality Level

200

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1 of 4

This Item
3140452423D8906
Dextran sulfate sodium salt from Leuconostoc spp. Mr ~500,000

Sigma-Aldrich

31395

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. Mr 5,000

Sigma-Aldrich

31404

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. low sulfate content, Mr ~40,000

Sigma-Aldrich

52423

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. Molecular Biology, average Mw >500,000 (dextran starting material), contains 0.5-2% phosphate buffer

Sigma-Aldrich

D8906

Dextran sulfate sodium salt from Leuconostoc spp.

biological source

(Leuconostoc spp.)

biological source

(Leuconostoc spp.)

biological source

(Leuconostoc spp)

biological source

synthetic

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

300

solubility

H2O: freely soluble 50 mg/mL, clear

solubility

H2O: 0.1 g/mL, clear, colorless to slightly yellow, water: 100 g/L at 25 °C (77 °F ), H2O: freely soluble 50 mg/mL, clear

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

H2O: 100 mg/mL

form

powder

form

powder

form

powder

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

-

cation traces

Ca: ≤200 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤1000 mg/kg, Mn: ≤5 mg/kg, Pb: ≤5 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Ni: ≤5 mg/kg, Cr: ≤5 mg/kg, Zn: ≤5 mg/kg, Mg: ≤100 mg/kg

cation traces

-

cation traces

-

cation traces

-

Application

Dextran sulfate sodium salt from Leuconostoc sp. was used as a test compound for studying the heparin and dextran sulphate interaction with alkali ions.[1] It was used for releasing DNA from DNA-histone complexes.[2]

Biochem/physiol Actions

Dextran is a mixture of glucose polymers of varying size and geometry. Dextran in the form of dextran sulfate acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength.[3][4]The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.[5][6]

Preparation Note

prepared from dextran with Mr ~500,000

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9956
BCCM9955
BCCM7872
BCCL4497
BCCL4240

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Prevention of venous thromboembolism.
G P Clagett et al.
Chest, 108(4 Suppl), 312S-334S (1995-10-01)
Simon Finfer et al.
The New England journal of medicine, 350(22), 2247-2256 (2004-05-28)
It remains uncertain whether the choice of resuscitation fluid for patients in intensive care units (ICUs) affects survival. We conducted a multicenter, randomized, double-blind trial to compare the effect of fluid resuscitation with albumin or saline on mortality in a
Stefano Casola
Methods in molecular biology (Clifton, N.J.), 271, 91-109 (2004-05-18)
Since its first application in mice almost 10 yr ago, the Cre/loxP has become the system of choice to study gene function in vivo in a cell-type, stage-specific, and inducible manner. This chapter provides a set of updated protocols that
Heparin and dextran sulfate antagonize PGI2 inhibition of platelet aggregation.
A Eldor et al.
Thrombosis research, 16(5-6), 617-628 (1979-01-01)
Lisa Nebelin Hvidt et al.
Danish medical journal, 59(11), A4531-A4531 (2012-11-23)
Synthetic colloids are frequently used in fluid resuscitation of septic patients. Despite this, little is known about the potential side effects including the risk of renal failure and bleeding. As practice has changed, we performed a before-and-after study of fluid
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