46232

Dipyron monohydrate

VETRANAL^®, analytical standard

• Synonym(s): Metamizol, Methapyrone
• Empirical Formula (Hill Notation): C₁₃H₁₆N₃NaO₄S · H₂O
• CAS Number: 5907-38-0
• Molecular Weight: 351.35
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329757107
• MDL number: MFCD00150293
• Beilstein/REAXYS Number: 3865381

Properties

• grade: analytical standard
• Quality Segment: 200
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): clinical; forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: O.[Na+].CN(CS([O-])(=O)=O)C1=C(C)N(C)N(C1=O)c2ccccc2
• InChI: 1S/C13H17N3O4S.Na.H2O/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;;/h4-8H,9H2,1-3H3,(H,18,19,20);;1H2/q;+1;/p-1
• InChI key: UNZIDPIPYUMVPA-UHFFFAOYSA-M
• Gene Information: human ... PTGS1(5742), PTGS2(5743)

Description

General description

Metamizol is an active pharmaceutical ingredient with both analgesic and antipyretic effects, primarily used to relieve pain caused by neuritis and neuralgia.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Metamizol may be used as a reference standard for the determination of metamizol in pharmaceutical formulations by reversed-phase high-performance liquid chromatography (RP-HPLC).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H361fd
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges