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45379

Supelco

Chlordecone

PESTANAL®, analytical standard

Synonym(s):

Kepone, Chlordecone, Perchloropentacyclo[5.3.0.02,6.03,9.04,8]decan-5-one

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About This Item

Empirical Formula (Hill Notation):
C10Cl10O
CAS Number:
143-50-0
Molecular Weight:
490.64
EC Number:
205-601-3
MDL number:
MFCD00213544
UNSPSC Code:
41116107
PubChem Substance ID:
329756686
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

ClC1(Cl)C2(Cl)C3(Cl)C4(Cl)C(=O)C5(Cl)C3(Cl)C1(Cl)C5(Cl)C24Cl

InChI

1S/C10Cl10O/c11-2-1(21)3(12)6(15)4(2,13)8(17)5(2,14)7(3,16)9(6,18)10(8,19)20

InChI key

LHHGDZSESBACKH-UHFFFAOYSA-N

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General description

Chlordecone is a chlorinated cyclodiene pesticide and a persistent environmental contaminant, obtained via degradation of mirex.

Application

Chlordecone may be used as an analytical reference standard for the quantification of the analyte in animals using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

H301 + H311,H351,H410

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8655
BCCB4861
SZBE073XV
SZBA243XV
SZBA243X

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Development and validation of an HPLC-MS/MS method with QuEChERS extraction using isotopic dilution to simultaneously analyze chlordecone and chlordecol in animal livers
Saint-Hilaire M, et al.
Food Chemistry, 252, 147-153 (2018)
Toxicological Study of Pesticides in Animals (1990)
High-performance liquid chromatography separation of chlordecone and its metabolites
Chromatographia, 22(1-6), 165-167 (1986)
Sophie Seurin et al.
Regulatory toxicology and pharmacology : RTP, 63(3), 471-479 (2012-06-12)
Chlordecone is an organochlorine insecticide used in the French West Indies until 1993. Toddlers are expected to be differently exposed than older children and adults. The dietary exposure to chlordecone of 18-month-old Guadeloupian toddlers was assessed through different scenarios depending
Fei Wang et al.
International immunopharmacology, 7(13), 1808-1812 (2007-11-13)
In murine models of systemic lupus erythematosus (SLE), administration of either prolactin or estradiol (E2) increases autoimmunity, and there is evidence that elevated prolactin in response to E2 administration may contribute substantially to E2 effects. Hormonal influence on SLE can
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