32472

Cefquinome sulfate

VETRANAL^®, analytical standard

• Synonym(s): (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sulfate, Cefquinome sulphate
• Empirical Formula (Hill Notation): C₂₃H₂₄N₆O₅S₂ · H₂SO₄
• CAS Number: 118443-89-3
• Molecular Weight: 626.68
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329754231
• MDL number: MFCD23381671
• Beilstein/REAXYS Number: 11333438

Properties

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OS([O-])(=O)=O.CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3cccc4CCCCc34)=C(N2C1=O)C(O)=O)c5csc(N)n5
• InChI: 1S/C23H24N6O5S2.H2O4S/c1-34-27-16(14-11-36-23(24)25-14)19(30)26-17-20(31)29-18(22(32)33)13(10-35-21(17)29)9-28-8-4-6-12-5-2-3-7-15(12)28;1-5(2,3)4/h4,6,8,11,17,21H,2-3,5,7,9-10H2,1H3,(H3-,24,25,26,30,32,33);(H2,1,2,3,4)/b27-16-;/t17-,21-;/m1./s1
• InChI key: KYOHRXSGUROPGY-OFNLCGNNSA-N

Description

General description

Cefquinome sulfates are veterinary, parenteral, fourth-generation cephalosporins belonging to the aminothiazolyl class of compounds. They exhibit broad-spectrum antimicrobial activity against gram-positive and gram-negative bacteria such as Pseudomonas aeruginosa and Enterobacteriaceae.[1]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Cefquinome sulfate may be used as an analytical reference standard for the determination of the analyte in:

• Pharmaceutical dosage form by reversed phase high performance liquid chromatography (RP-HPLC).[1]

It may be used as a precursor for the preparation of cefquinome that can be employed as an analytical reference standard for the analysis of the analyte in:

• Bovine milk as well as muscle and kidney samples by HPLC and LC coupled to tandem mass spectrometry (MS/MS), respectively.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08,GHS07,GHS09
• signalword: Danger
• hcodes: H315,H319,H334,H335,H410
• pcodes: P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3