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2106

Heparin sodium salt from porcine intestinal mucosa

endotoxin, free

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Size/SKUAvailabilityPrice
10 vials
Please contact Customer Service for Availability
PLN 286.00
15 vials
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PLN 426.00

About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.21
MDL number:

PLN 286.00


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biological source

Porcine intestinal mucosa

Quality Segment

form

powder

usage

sufficient for 5 mL blood anticoagulant

packaging

preweighed vial of 300 USP units

impurities

endotoxin, free

color

beige

solubility

water: soluble 50 g/L, acetone: insoluble, alcohol: insoluble, benzene: insoluble, chloroform: insoluble, diethyl ether: insoluble

compatibility

for use with E-Toxate

storage temp.

room temp

SMILES string

[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O

InChI

1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-

InChI key

JRTRSJGZMRQDHI-UHFFFAOYSA-N

Application

Heparin sodium salt from porcine intestinal mucosa has been used as a M199 medium supplement used for maintaining human umbilical vein endothelial cells.[1]

Biochem/physiol Actions

Heparin sodium salt is the salt form of heparinic acid and is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is an anticoagulant that produces its major anticoagulant effect by activating antithrombin. Heparin binds to antithrombin III, a naturally occurring plasma protease inhibitor and accelerates significantly the rate at which antithrombin III (AT-III) inhibits coagulation proteases (factor Xa and thrombin).[2][3][4] Additionally, it also facilitates the stabilization and regulation of tryptase as an enzymatically active tetramer.[5]

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Legal Information

E-Toxate is a trademark of Sigma-Aldrich Co. LLC

Disclaimer

Not for injection.

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1 of 1

This Item
H3149H3393375095
biological source

Porcine intestinal mucosa

biological source

Porcine intestinal mucosa

biological source

Porcine intestinal mucosa

biological source

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

solubility

water: soluble 50 g/L, alcohol: insoluble, chloroform: insoluble, acetone: insoluble, diethyl ether: insoluble, benzene: insoluble

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

solubility

water: 50 mg/mL

form

powder

form

powder

form

powder

form

lyophilized

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

15-25°C

impurities

endotoxin, free

impurities

-

impurities

-

impurities

-


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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–2 of 2 Questions  
  1. What is the molecular weight of Heparin sodium salt? Is this same with cat:H3149 or H3393?

    1 answer
    1. The molecular weight of porcine Heparin sodium may range from 6,000 to 30,000 Daltons, with most chains ranging from 16,000–19,000 Da. This product, as well as the H3393 and H3149, are derived from the same source and offer identical properties, including molecular weight.

      Helpful?

  2. Hola, Me gustaría saber cual es la cantidad de heparina en cada uno de los viales

    1 answer
    1. The minimum activity of this heparin product is 300 units per vial. This product is lyophilized from a prepared stock solution and the mass weight per vial is not available. However, the starting material used to produce this product has historically tested at approximately 200 units heparin per milligram. The mass weight per vial is expected to reflect this value, with each 300 unit vial containing approximately 1.5 mg.

      Helpful?

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