08984

Butyryl-L-carnitine

analytical standard

• Synonym(s): (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxobutoxy)-1-propanaminium inner salt, Butanoyl-L-carnitine, C4-Carnitine
• Empirical Formula (Hill Notation): C₁₁H₂₁NO₄
• CAS Number: 25576-40-3
• Molecular Weight: 231.29
• UNSPSC Code: 41116107
• NACRES: NB.21
• MDL number: MFCD01674827

Properties

• grade: analytical standard
• Quality Segment: 100
• assay: ≥97.0% (HPLC)
• optical activity: [α]/D -23.0±2.0°, c = 0.1 in H₂O
• shelf life: limited shelf life, expiry date on the label
• impurities: ≤10.0% water
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(CCC)=O)CC([O-])=O
• InChI: 1S/C11H21NO4/c1-5-6-11(15)16-9(7-10(13)14)8-12(2,3)4/h9H,5-8H2,1-4H3/t9-/m1/s1
• InChI key: QWYFHHGCZUCMBN-SECBINFHSA-N

Description

General description

Butyryl-L-carnitine is a naturally occurring compound belonging to the acylcarnitine class of compounds as listed in the human metabolome database (HMBD). These compounds are reported to be used as biomarkers in the diagnosis of carnitine deficiency. It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

Application

Butyryl-L-carnitine may be used as an analytical reference standard for the separation and identification of underivatized butyryl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS). It may also be used as an analytical reference standard for the quantification of the analyte in biological samples[1] using chromatography-based techniques.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable