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03641

Dansyl chloride

LiChropur, ≥99.0% (HPLC)

Synonym(s):

5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl

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Size/SKUAvailabilityPrice
100 mg
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PLN 210.00
10 x 100 mg
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PLN 1,480.00

About This Item

Empirical Formula (Hill Notation):
C12H12ClNO2S
CAS Number:
Molecular Weight:
269.75
UNSPSC Code:
41116105
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-092-6
Beilstein/REAXYS Number:
2217205
MDL number:

PLN 210.00


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grade

derivatization grade ((HPLC))

Quality Segment

assay

≥99.0% (HPLC)

form

powder or crystals

quality

LiChropur

technique(s)

HPLC: suitable

mp

72-74 °C (lit.)

solubility

acetone: 0.2 g/10 mL, clear to slightly turbid, yellow to very dark yellow-orange

storage temp.

2-8°C

SMILES string

CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O

InChI

1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3

InChI key

XPDXVDYUQZHFPV-UHFFFAOYSA-N

General description

Dansyl chloride is a fluorogenic reagent which is typically employed for the derivatization of amino acids.

Application

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.
Dansyl chloride has been used for the fluorogenic labeling of xenoestrogens, 4-nonylphenol and bisphenol A prior to their determination by high-performance liquid chromatography (HPLC) with fluorescence detection. It has also been used for the derivatization of icariin in human serum samples after oral administration of Epimedium decoction, followed by its determination using ultrasensitive LC-tandem mass spectrometry (LC-MS) and for the derivatization of antitumoral agent ES-285 in dog plasma followed by its analysis by HPLC equipped with ultraviolet and fluorescence detection.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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This Item
39220D262539068
technique(s)

HPLC: suitable

technique(s)

-

technique(s)

-

technique(s)

-

grade

derivatization grade ((HPLC))

grade

-

grade

-

grade

-

assay

≥99.0% (HPLC)

assay

≥99.0% (HPLC)

assay

≥99% (HPLC)

assay

≥97.5% (AT)

solubility

acetone: 0.2 g/10 mL, clear to slightly turbid, yellow to very dark yellow-orange

solubility

acetone: 0.2 g/10 mL

solubility

acetone: 20 mg/mL

solubility

DMF: soluble, acetonitrile: soluble

quality

LiChropur

quality

-

quality

-

quality

-

form

powder or crystals

form

powder

form

powder and chunks

form

-


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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