The recombinant protein does not have a histidine tag. The amino acids sequence is
AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL.
GF177
APRIL, Human Recombinant
Synonym(s):
Tumor necrosis factor ligand superfamily member 13, TALL2, ZTNF2
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
10 μg | Available to ship TODAYfromKuehne + Nagel Sp. z o.o. | PLN 1,450.00 |
About This Item
UNSPSC Code:
12352200
NACRES:
NA.77
eCl@ss:
32160405
General description
APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor.
Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.
Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.
Product Source: Protein is expressed in E.coli.
Application
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Physical form
Product is presented in 10 mM Sodium Phosphate, pH 7.5 + 500 mM NaCl + 5% Trehalose and is filtered through a 0.2 micron filter before lyophilization.
Preparation Note
Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Analysis Note
Measured by its ability to induce cell death in Jurkat cells.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
1 of 1
This Item | |||
|---|---|---|---|
| UniProt accession no. | UniProt accession no. | UniProt accession no. - | UniProt accession no. |
| impurities <0.1 μg/mg protein endotoxin (<1 EU/μg) | impurities <0.1 μg/mg protein endotoxin (<1EU/μg) | impurities <1.0 EU/μg protein Endotoxin | impurities <0.1 EU/μg endotoxin, tested |
| shipped in dry ice | shipped in dry ice | shipped in ambient | shipped in wet ice |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
Storage Class
13 - Non Combustible Solids
wgk
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
-
Cual es la secuencia de esta proteína recombinante? Lleva histidinas? En qué extremo N-T o C-T?
1 answer-
Helpful?
-