AB5864

Anti-Myelin Basic Protein Antibody

CHEMICON^®, rabbit polyclonal

• Synonym(s): MBP
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• Clone: polyclonal
• Species reactivity: human, rat
• Application: IHC
• Citations: 75

Properties

• Product Name: Anti-Myelin Basic Protein Antibody, serum, Chemicon^®
• biological source: rabbit
• Quality Segment: 100
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human, rat
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable
• NCBI accession no.: NM_001025081.1, NM_001025090.1, NM_001025092.1, NM_001025094.1, NM_001025098.1, NM_001025100.1, NM_001025101.1, NM_002385.2
• UniProt accession no.: P02686
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... MBP(4155) ; rat ... Mbp(24547)

Description

Immunogen

Synthetic peptide corresponding to amino acids 69-86 of the guinea pig protein. Immunogen corresponds to "degraded" Myelin Basic Protein: YGSLPQKSQRSQDENPVV

Application

Anti-Myelin Basic Protein Antibody is an antibody against Myelin Basic Protein for use in IH.

Immunohistochemistry: 1:2,000. Immunostains myelin basic protein of abnormal appearing oligodendrocytic processes and cell bodies in demyelinating areas. The antibody recognizes only areas of myelin degeneration when tested in injured spinal cord and lesioned sciatic nerve. It also stains discrete white matter in brain of multiple system atrophy

Optimal working dilutions must be determined by the end user.

Research Category
Neuroscience

Research Sub Category
Neuronal & Glial Markers

Neurodegenerative Diseases

Biochem/physiol Actions

Recognizes Myelin Basic Protein in demyelinated nerve tissues. Immunohistochemistry analysis of lesioned rat spinal cord shows a high level of specificity for this antiserum.

Physical form

Rabbit Serum. Lyophilized, no preservatives. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any residue.

Unpurified

Preparation Note

Maintain at -20 to -70°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. Glycerol (1:1) can be added for additional stability.

Analysis Note

Control
Brain tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable