8.55126

NovaPEG amino resin

Novabiochem^®

• UNSPSC Code: 51171641

Properties

• Quality Segment: 200
• product line: NovaPEG, Novabiochem^®
• form: beads
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: amine
• storage temp.: 2-8°C

Description

General description

A remarkable totally PEG-based resin for solid phase peptide synthesis. The support has excellent swelling properties in a wide range of solvents, including water, MeCN, MeOH, DCM, DMF, THF, and toluene. In comparative studies this resin was found to give better results than polystyrene-based supports in the synthesis of hydrophobic peptides. The high hydrophilicity was also found to benefit on-resin immunoassays with one-bead-one-peptide libraries ^[1].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

^[1] F. Garcia-Martin, et al. (2006) J. Comb. Chem., 8, 213.

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.45 - 1.00 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result

Other Notes

Replaces: 01-64-0485

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_c: Not applicable
• flash_point_f: Not applicable