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8.55026

Sigma-Aldrich

4-Benzyloxybenzaldehyde polystyrene HL

Novabiochem®

Synonym(s):

Aldehyde Wang HL resin

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About This Item

UNSPSC Code:
13111023
NACRES:
NA.22

Quality Level

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

alcohol

storage temp.

2-8°C

General description

This support is an excellent tool for the production of sulfonamides and anilides by SPOS [1]. Amines have been released from this resin with DDQ [2] and tertiary amides by acylation of resin-bound secondary amines with acid chlorides [3].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] B. Raju & T. P. Kogan (1997) Tetrahedron Lett., 38, 4965.
[2] S. Kobayashi & Y. Aoki (1998) Tetrahedron Lett., 39, 7345.
[3] M. W. Miller, et al. (1998) Tetrahedron Lett., 39, 3429.

Linkage

Replaces: 01-64-0182

Analysis Note

Color (visual): white to yellow to orange
Appearance of substance (visual): beads
Loading (determined by elemental analysis of sulfur after derivatization with tosylhydrazide): 2.0 - 3.5 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly(styrene - 2% DVB), 200 -400 mesh.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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