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426205

β-Lactamase, Bacillus cereus 569/H9

Synonym(s):

β-Lactamase, Bacillus cereus 569/H9, Penicillinase

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Size/SKUAvailabilityPrice
500 U

Available to ship TODAYfromKuehne + Nagel Sp. z o.o.

PLN 556.00

About This Item

CAS Number:
EC Number:
UNSPSC Code:
12352202
NACRES:
NA.54
MDL number:
Biological source:
Bacillus sp. (Bacillus cereus)

PLN 556.00


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biological source

Bacillus sp. (Bacillus cereus)

Quality Segment

description

Merck USA index - 14, 7093

form

lyophilized

packaging

vial of ≥50 units β-lactamase II, vial of ≥500 units β-lactamase I

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

sterile distilled water: soluble

shipped in

ambient

storage temp.

−20°C

General description

β-Lactamase produced by bacteria shares sequence homology to penicillin-binding proteins.[1] This enzyme is found in Gram-negative bacteria.[2] β-Lactamases have four molecular classes, named A, B, C, and D. A, C, and D form an acyl-enzyme via active site serine residue. Class B β-lactamases are metalloenzymes, which have a zinc ion at their active site for β-lactam hydrolysis.[3]

Biochem/physiol Actions

β-Lactamase hydrolyzes β-lactum antibiotics and is the chief cause of resistance to β-lactam antibiotics development by bacteria.[1][3] Mutations in the β-lactamases are associated with extended-spectrum β-lactamases (ESBLs).[4]

Preparation Note

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 month at 4°C.

Other Notes

One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol benzyl penicillin and 1.0 µmol of cephalosporin C, respectively, per min at 25°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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This Item
P452421947591274
biological source

Bacillus sp. (Bacillus cereus)

biological source

bacterial (Enterobacter cloacae)

biological source

-

biological source

-

form

lyophilized

form

lyophilized powder

form

powder

form

liquid

shipped in

ambient

shipped in

-

shipped in

ambient

shipped in

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

sterile distilled water: soluble

solubility

-

solubility

25 mM phosphate buffer, pH 7.0: 2.5 mg/mL, methanol: 50 mg/mL

solubility

-

storage condition

OK to freeze

storage condition

-

storage condition

OK to freeze

storage condition

-


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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