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182015

Cyclo(Arg-Gly-Asp-D-Phe-Val)

Potent inhibitor of cell adhesion.

Synonym(s):

Cyclo(Arg-Gly-Asp-D-Phe-Val), RGDFV Peptide, Cyclic

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Size/SKUAvailabilityPrice
1 mg

Estimated to ship onJune 03, 2026fromKuehne + Nagel Sp. z o.o.

PLN 1,090.00

About This Item

Empirical Formula (Hill Notation):
C26H38N8O7
CAS Number:
137813-35-5
Molecular Weight:
574.63
MDL number:
MFCD00008159
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥95% (HPLC)
Form:
solid
Storage condition:
OK to freeze, desiccated (hygroscopic)

PLN 1,090.00

Estimated to ship onJune 03, 2026Details

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Quality Segment

100

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

1 N acetic acid: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

Potent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion. Inhibits the redistribution of c-Src into focal adhesions, thereby leading to impaired MAP Kinase activation.

Biochem/physiol Actions

Cell permeable: no
Primary Target
inhibits tumor cell adhesion to laminin and vitronectin substrates
Product does not compete with ATP.
Reversible: no

Other Notes

Shono, T., et al. 2001. Exp. Cell Res.268, 169.
Matsuno, H., et al. 1994. Circulation 90, 2203.
Noiri, E., et al. 1994. Kidney Int. 46, 1050.
Gurrath, M., et al. 1992. Eur. J. Biochem. 210, 911.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Cyclo(Arg-Gly-Asp-D-Phe-Val) Potent inhibitor of cell adhesion.

Sigma-Aldrich

182015

Cyclo(Arg-Gly-Asp-D-Phe-Val)

GGACK An irreversible inhibitor of urokinase (IC50 1 µM) and Factor Xa.

Sigma-Aldrich

347436

GGACK

Nrf2 Activator III, TAT-14 Peptide The Nrf2 Activator III, TAT-14 Peptide modulates the biological activity of Nrf2. This small molecule/inhibitor is primarily used for Biochemicals applications.

Sigma-Aldrich

492042

Nrf2 Activator III, TAT-14 Peptide

Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable The Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Sigma-Aldrich

189485

Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable

assay

≥95% (HPLC)

assay

≥80% (HPLC)

assay

≥95% (HPLC)

assay

≥97% (HPLC)

form

solid

form

solid

form

powder

form

lyophilized solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

1 N acetic acid: 5 mg/mL

solubility

water: 50 mg/mL

solubility

DMSO: 100 mg/mL

solubility

5% acetic acid: 1 mg/mL, water: 1 mg/mL, DMSO: 5 mg/mL

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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