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870262C

Avanti

18:1 Dodecanyl PE

Avanti Research™ - A Croda Brand 870262C

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanyl) (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C53H97NO11PNa
CAS Number:
474923-47-2
Molecular Weight:
978.30
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (870262C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870262C

concentration

10 mg/mL (870262C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCN([H])C(CCCCCCCCCCC(O)=O)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C53H98NO11P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-31-35-39-43-52(58)62-47-49(65-53(59)44-40-36-32-26-24-22-20-18-16-14-12-10-8-6-4-2)48-64-66(60,61)63-46-45-54-50(55)41-37-33-29-27-28-30-34-38-42-51(56)57;/h17-20,49H,3-16,21-48H2,1-2H3,(H,54,55)(H,56,57)(H,60,61);/q;+1/p-1/b19-17-,20-18-;/t49-;/m1./s1

InChI key

AHHCDNFLXOEQMC-VXILFBGRSA-M

General description

18:1 Dodecanyl PE, also known as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanoyl) is a head group modified functionalized lipid. Functionalized lipids act as reporter molecules.

Application

18:1 Dodecanyl PE or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-dodecanoyl may be used as a component of fusogenic liposome formulation. It may also be used in unilamellar liposome preparation.

Packaging

5 mL Clear Glass Sealed Ampule (870262C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rico C Gunawan et al.
Biomaterials, 31(5), 900-907 (2009-11-03)
Targeted drug delivery to inflamed or injured vascular endothelial cells (ECs) and smooth muscle cells (SMCs) may provide a precise and effective therapeutic treatment for cardiovascular diseases. Upregulation of cytokine-regulated cell surface receptors, intercellular cell adhesion molecule-1 (ICAM) and endothelial-leukocyte
T Shangguan et al.
Gene therapy, 7(9), 769-783 (2000-05-24)
A unique method for formulation of plasmid DNA with phospholipids has been devised for the purpose of producing vehicles that can mediate gene delivery and transfection of living cells. The polycation, spermine, was used to condense plasmid DNA within a
Mariusz Kepczynski et al.
Biochimica et biophysica acta, 1858(10), 2362-2379 (2016-03-08)
Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as

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