Skip to Content
Merck
All Photos(1)

Documents

860636P

Avanti

Glucosyl(β) Sphingosine-d5

Avanti Research - A Croda Brand

Synonym(s):

D-glucosyl-β-1,1′-D-erythro-sphingosine-d5

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C24H42D5NO7
CAS Number:
Molecular Weight:
466.66
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (860636P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCC([2H])(C([2H])([2H])[2H])[2H])(O)[C@](N)([H])CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

Application

Glucosyl(β) Sphingosine-d5 has been used as an internal standard for the quantification of lysohexosylceramide in various samples by liquid chromatography-tandem mass spectrometry.

Biochem/physiol Actions

Glucosyl sphingosine has an ability to regulate Ca2+ release in the brain microsomes. It acts as a potential biomarker for Gaucher disease (GD).

Packaging

5 mL Amber Glass Screw Cap Vial (860636P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: a novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease
Pettazzoni M, et al.
Testing, 12(7) (2017)
LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: a novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease
Pettazzoni M, et al.
PLoS ONE, 12(7) (2017)
Glucosylsphingosine is a highly sensitive and specific biomarker for primary diagnostic and follow-up monitoring in Gaucher disease in a non-Jewish, Caucasian cohort of Gaucher disease patients
Rolfs A, et al.
PLoS ONE, 8(11) (2013)
Mercedes Roca-Espiau et al.
Journal of orthopaedic surgery and research, 14(1), 383-383 (2019-11-23)
Chronic fatigue (CFg) is a prevalent symptom in Gaucher disease (GD) at diagnosis (79%) and remains in a quarter of patients after years of therapy. Bone abnormalities are present in over 70% and peripheral neuropathy in about 11% of the
Muscle-tendon weakness contributes to chronic fatigue syndrome in Gaucher?s disease
Roca-Espiau M, et al.
Journal of Orthopaedic Surgery and Research, 14(1), 383-383 (2019)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service