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790595P

Avanti

Upstate Lipid Blend

Synthetic Phospholipid Blend for PTEN, PDK1, and Akt1/PKBα Assay Kits, contains DOPC/DOPS (1:1, wt%), powder

Synonym(s):

Upstate Lipid Blend, Assay kits formerly supplied by Upstate Biotechnology.

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (790595P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 790595P

lipid type

formulation
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

Upstate lipid blend comprises DOPC:DOPS in the ratio 1:1wt%. 1,2-dioleoyl-sn-glycero-3-phosphocholine(DOPC) and 1,2-dioleoyl-sn-glycero-3-[phospho-l-serine] (DOPS) are crucial eukaryotic plasma membrane components.

Application

Upstate lipid blend has been used in the generation for L-α-phosphatidylinositol (PI):DOPS:DOPC in phosphatidylinositol 4-kinase β (PI4Kβ) and phosphoinositide 3-kinase β (PI3Kβ) activity studies.

Biochem/physiol Actions

1,2-dioleoyl-sn-glycero-3-phosphocholine(DOPC) and 1,2-dioleoyl-sn-glycero-3-[phospho-l-serine] (DOPS) bilayers are stable and are used in generating multilamellar vesicles.

Packaging

5 mL Amber Glass Screw Cap Vial (790595P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Molecular volumes of DOPC and DOPS in mixed bilayers of multilamellar vesicles
Murugova TN and Balgavy P
Physical Chemistry Chemical Physics, 16(34), 18211-18216 (2014)
Multistep compositional remodeling of supported lipid membranes by interfacially active phosphatidylinositol kinases
Tabaei SR, et al.
Analytical Chemistry, 88(10), 5042-5045 (2016)
Characterization of the interface of binary mixed DOPC: DOPS liposomes in water: The impact of charge condensation
Lutgebaucks C, et al.
J. Chem. Phys. , 146(4), 044701-044701 (2017)
Design and structural characterization of potent and selective inhibitors of phosphatidylinositol 4 kinase IIIbeta
Rutaganira FU, et al.
Journal of Medicinal Chemistry, 59(5), 1830-1839 (2016)

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