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284025

Sigma-Aldrich

Diethylenetriaminepentaacetic dianhydride

98%

Synonym(s):

N,N-Bis[2-(2,6-dioxomorpholino)ethyl]glycine, DTPA anhydride, DTPA dianhydride

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O8
CAS Number:
Molecular Weight:
357.32
Beilstein:
1230954
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Assay

98%

form

powder

mp

182-184 °C (lit.)

storage temp.

−20°C

SMILES string

OC(=O)CN(CCN1CC(=O)OC(=O)C1)CCN2CC(=O)OC(=O)C2

InChI

1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)

InChI key

RAZLJUXJEOEYAM-UHFFFAOYSA-N

Application

Employed in the synthesis of macrocyclic ligands and lanthanide complexes that are useful as MRI enhancers.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yongbo Yang et al.
ACS applied materials & interfaces, 9(28), 23450-23457 (2017-06-29)
A bimodal contrast nanoagent was developed by chelating gadolinium ions to 2-[bis[2-[carboxymethyl-[2-oxo-2-(2-sulfanylethyl-amino)ethyl]amino]ethyl]amino]acetic acid (DTDTPA)-modified CuInS
Inorganic Chemistry, 33, 5794-5794 (1994)
Farid N Faruqu et al.
Theranostics, 9(6), 1666-1682 (2019-05-01)
Extracellular vesicles, in particular exosomes, have recently gained interest as novel drug delivery vectors due to their biological origin and inherent intercellular biomolecule delivery capability. An in-depth knowledge of their in vivo biodistribution is therefore essential. This work aimed to
Yuanyuan Li et al.
Theranostics, 7(19), 4689-4698 (2017-12-01)
Biodegradable polymeric nanomaterials can be directly broken down by intracellular processes, offering a desirable way to solve toxicity issues for cancer diagnosis and treatment. Among them, aliphatic polycarbonates are approved for application in biological fields by the United States Food
B M Kinsey et al.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 15(3), 285-292 (1988-01-01)
We have developed a simple, rapid, and reproducible method for conjugating the bifunctional metal chelator diethylenetriaminepentaacetic acid (DTPA) to an IgM monoclonal antibody (MoAb) without first isolating the MoAb from the ascites fluid. Treatment of the protein mixture in the

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