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192279

Sigma-Aldrich

1-Amino-1-cyclopentanemethanol

97%

Synonym(s):

Cycloleucinol

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About This Item

Linear Formula:
H2NC5H8CH2OH
CAS Number:
10316-79-7
Molecular Weight:
115.17
EC Number:
233-697-7
MDL number:
MFCD00010491
UNSPSC Code:
12352100
PubChem Substance ID:
24851536
NACRES:
NA.22

Assay

97%

bp

85-90 °C/10 mmHg (lit.)

mp

20 °C (lit.)

functional group

hydroxyl

SMILES string

NC1(CO)CCCC1

InChI

1S/C6H13NO/c7-6(5-8)3-1-2-4-6/h8H,1-5,7H2

InChI key

PDNZJLMPXLQDPL-UHFFFAOYSA-N

Application

1-Amino-1-cyclopentanemethanol was used in the synthesis of xanthine-derived heterocyclic fused systems. It was also used as building block in medicinal chemistry synthesis.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

204.8 °F - closed cup

Flash Point(C)

96 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBC0244V
13726DH
09117PE
14025BD
10213LG

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Paul V Fish et al.
Journal of medicinal chemistry, 50(10), 2341-2351 (2007-04-24)
1-isoquinolinylguanidines were previously disclosed as potent and selective inhibitors of urokinase-type plasminogen activator (uPA). Further investigation of this template has revealed that incorporation of a 7-sulfonamide group furnishes a new series of potent and highly selective uPA inhibitors. Potency and
Methods for the synthesis of xanthine-derived polycyclic fused systems.
Szymanska E, et al.
Heterocyclic Communications, 19(5), 297-310 (2013)
David C Pryde et al.
Journal of medicinal chemistry, 49(14), 4409-4424 (2006-07-11)
Female sexual arousal disorder (FSAD) is a highly prevalent sexual disorder affecting up to 40% of women. We describe herein our efforts to identify a selective neutral endopeptidase (NEP) inhibitor as a potential treatment for FSAD. The rationale for this

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