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MG500

Sigma-Aldrich

May-Grünwald Stain

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About This Item

MDL number:
UNSPSC Code:
41116121
NACRES:
NA.47

form

solution

shelf life

Expiry date on the label.

IVD

for in vitro diagnostic use

concentration

0.25 % (w/v) in methanol

application(s)

hematology
histology

storage temp.

room temp

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General description

May-Grünwald Stain has been employed to stain neutrophil granules and granulocyte inclusion bodies. May-Grünwald-Giemsa might be useful in the diagnosis of Malassezia folliculitis, a fungal mediated disorder.

Application

For use in the differential staining of cellular elements of blood

Preparation Note

Prepared with non-polychromed (non-oxidized) methylene blue and eosin Y.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup


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Sunmi Park et al.
PLoS genetics, 13(9), e1006991-e1006991 (2017-09-15)
Patients with mutations of the THRA gene exhibit classical features of hypothyroidism, including erythroid disorders. We previously created a mutant mouse expressing a mutated TRα1 (denoted as PV; Thra1PV/+ mouse) that faithfully reproduces the classical hypothyroidism seen in patients. Using
Historical hematology: May--Hegglin anomaly
Saito, Hidehiko and Kunishima, Shinji
American Journal of Hematology, 83(4) (2008)
Ashkan Ojaghi et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(26), 14779-14789 (2020-06-21)
Hematological analysis, via a complete blood count (CBC) and microscopy, is critical for screening, diagnosing, and monitoring blood conditions and diseases but requires complex equipment, multiple chemical reagents, laborious system calibration and procedures, and highly trained personnel for operation. Here
Resveratrol induces human K562 cell apoptosis, erythroid differentiation, and autophagy.
Yan HW, Hu WX, Zhang JY, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 35(6), 5381-5388 (2014)
Epidemiological characteristics of Malassezia folliculitis and use of the May-Grunwald-Giemsa stain to diagnose the infection
Durdu, et al.
Diagnostic Microbiology and Infectious Disease, 76(4) (2013)

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