Skip to Content
Merck
All Photos(1)

Documents

MAK553

Sigma-Aldrich

Fluorimetric cADP-Ribose Assay Kit

sufficient for 100 fluorometric tests

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41116104
NACRES:
NA.84

detection method

fluorometric

relevant disease(s)

genitourinary disorders; neurological disorders; cardiovascular diseases; cancer

shipped in

dry ice

storage temp.

−20°C

General description

cADP-ribose (cADPR) is a novel Ca2+ messenger derived from NAD+. ADP-riboxyl cyclase (ADPRC) catalyzes the synthesis of cADPR from NAD+, but the reaction can be reversed in the presence of high concentration of nicotinamide, producing NAD+ from cADPR stoichiometrically. The resultant NAD+ can be detected by the NAD probe. This makes monitoring cADPR in tissues and cell cultures possible in the low nM range. The NAD+ detection using NAD probe is specific to NAD+ and has no reaction to NADH. This assay can be performed in a convenient 96-well or 384-well microplate.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service