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10830

Sigma-Aldrich

(+)-Arabinogalactan

≥80% (HPLC), from larch wood

Synonym(s):

Polyarabinogalactan

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About This Item

CAS Number:
9036-66-2
EC Number:
232-910-0
MDL number:
MFCD00062638
UNSPSC Code:
12352201
NACRES:
NA.25
Pricing and availability is not currently available.

biological source

larch wood

Assay

≥80% (HPLC)

form

solid

impurities

≤15% water

color

white to beige

mp

>200 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear to slightly turbid, colorless to slightly brownish-yellow

storage temp.

room temp

SMILES string

O1C(C(C(C(C1COC3OCC(C(C3O)OC)O)O)OC)O)OC2C(C(OC(C2O)C)CO)O

InChI

1S/C20H36O14/c1-7-11(23)18(12(24)9(4-21)32-7)34-20-15(27)17(29-3)13(25)10(33-20)6-31-19-14(26)16(28-2)8(22)5-30-19/h7-27H,4-6H2,1-3H3

InChI key

SATHPVQTSSUFFW-UHFFFAOYSA-N

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Application

Larch Arabinogalactan, a plant-derived biopolymer, is an excellent dietary fiber that has been shown to increase the production of short-chain fatty acids, principally butyrate and propionate, and to decrease the generation and absorption of ammonia. Larch arabinogalactan can stimulate natural killer (NK) cell cytotoxicity, enhance other functional aspects of the immune system, and inhibit the metastasis of tumor cells to the liver.

Biochem/physiol Actions

Dietary fiber that enhances immune system function by stimulating natural killer (NK) cell activity.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCM3799
MKCJ9340
MKBT8488V
MKBZ9201V
MKBP9434V

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Arabinogalactan, a plant polysaccharide, as a new tool for pharmacon clathration.
T G Tolstikova et al.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 433, 247-248 (2010-08-17)
Susi Burgalassi et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 23(6), 541-550 (2007-11-16)
The aim of the present study was to investigate the corneal protective and healing properties of arabinogalactan (AG), a natural polysaccharide present in conifers of the genus Larix (Larch). AG was tested in comparison with other two polysaccharides possessing well-established
G S Kelly
Alternative medicine review : a journal of clinical therapeutic, 4(2), 96-103 (1999-05-08)
Larch arabinogalactan is composed of greater than 98-percent arabinogalactan, a highly branched polysaccharide consisting of a galactan backbone with side-chains of galactose and arabinose sugars. Larch arabinogalactan is an excellent source of dietary fiber, and has been approved as such
Xiaoge Gao et al.
Glycoconjugate journal, 29(4), 159-165 (2012-05-09)
The pH-modified citrus pectin (MCP) has been demonstrated to inhibit galectin-3 in cancer progression. The components and structures of MCP related to this inhibition remained unknown. In this paper, we fractionated MCP on DEAE-cellulose column into a homogenous neutral fraction
Cristiane H Baggio et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 67(7-8), 405-410 (2012-09-29)
Type II arabinogalactan (AG) is a polysaccharide found in Maytenus ilicifolia (Celastraceae), a plant reputed as gastroprotective. Oral and intraperitoneal administration of the AG protected rats from gastric ulcers induced by ethanol. No alteration of mechanisms related to acid gastric
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Questions

1–4 of 4 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What are the reported dimensions of the molecule?

    1 answer

    1. The dimensions of the molecule is not determined.

      Helpful?

  4. Could you tell me how large the arabinogalactan we are using is in kDa?

    1 answer

    1. The molecular weight is not determined. However, the literature suggests the molecular weight ranges between 72 - 92 kDa.

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