Skip to Content
Merck
All Photos(1)

Documents

535140

Millipore

Protease Inhibitor Cocktail III

Animal-Free, liquid, for the inhibition of aspartic, cysteine, serine proteases and aminopeptidases

Synonym(s):

Animal free Protease inhibitor

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352200
NACRES:
NA.54

product name

Protease Inhibitor Cocktail Set III, Animal-Free, Protease Inhibitor Cocktail Set III, Animal-Free, is a cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine & serine proteases & aminopeptidases.

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−20°C

General description

A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases. This cocktail is recommended for use with mammalian cell and tissue extracts. Each vial contains 100 mM AEBSF, HCl (Cat. No. 101500), 80 µM Aprotinin (Cat. No. 616371), 5 mM Bestatin (Cat. No. 200484), 1.5 mM E-64 (Cat. No. 324890), 2 mM Leupeptin Hemisulfate (Cat. No. 108975) and 1 mM Pepstatin A (Cat. No. 516482). Available as 1 ml vial or a set of 5 x 1 ml.
A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases. This cocktail is recommended for use with mammalian cell and tissue extracts. One ml is sufficient for approximately 20 g tissue. Note: 1 set = 5 x 1 ml vials.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Aspartic, cysteine, and serine proteases as well as aminopeptidases
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Irritant (B)

Physical form

In 1 ml DMSO.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

188.6 °F

Flash Point(C)

87 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Li-Ping Gao et al.
ACS chemical neuroscience, 11(5), 814-829 (2020-02-13)
Mitophagy is an important process for removing damaged mitochondria in cells, the dysfunction of which has been directly linked to an increasing number of neurodegenerative disorders. However, the details of mitophagy in prion diseases still need to be deeply explored.
Ching-Hsin Huang et al.
Advanced therapeutics, 3(6) (2021-03-02)
Mono- or dual-checkpoint inhibitors for immunotherapy have changed the paradigm of cancer care; however, only a minority of patients responds to such treatment. Combining small molecule immuno-stimulators can improve treatment efficacy, but they are restricted by poor pharmacokinetics. In this
Jia Chen et al.
Virologica Sinica, 35(5), 614-625 (2020-04-22)
Activation of inflammatory cells and upregulations of a number of cytokines in the central nervous system (CNS) of patients with prion diseases are frequently observed. To evaluate the potential changes of some brain cytokines that were rarely addressed during prion
Sungsin Jo et al.
Arthritis research & therapy, 23(1), 301-301 (2021-12-10)
WNT16 is critical for bone homeostasis, but the effect of WNT16 in ankylosing spondylitis (AS) is still unknown. Here, we investigated whether WNT16 influences bone formation and pathophysiological changes of AS in an in vitro model. The bone tissue from
Dong-Min Kim et al.
Cell reports, 37(1), 109798-109798 (2021-09-30)
Despite the worldwide effect of the coronavirus disease 2019 (COVID-19) pandemic, the underlying mechanisms of fatal viral pneumonia remain elusive. Here, we show that critical COVID-19 is associated with enhanced eosinophil-mediated inflammation when compared to non-critical cases. In addition, we

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service