Skip to Content
Merck
All Photos(1)

Documents

292087

Sigma-Aldrich

1-Chloro-2-propanol

70%

Synonym(s):

Chloropropanol, Propylene chlorohydrin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CH(OH)CH2Cl+CH3CHClCH2OH
CAS Number:
127-00-4
Molecular Weight:
94.54
Beilstein:
773653
EC Number:
204-819-6
MDL number:
MFCD00004530
UNSPSC Code:
12352100
PubChem Substance ID:
24857557
NACRES:
NA.22

Assay

70%

impurities

<25% 2-chloro-1-propanol

refractive index

n20/D 1.439 (lit.)

bp

126-127 °C (lit.)

density

1.111 g/mL at 25 °C (lit.)

SMILES string

CC(O)CCl

InChI

1S/C3H7ClO/c1-3(5)2-4/h3,5H,2H2,1H3

InChI key

YYTSGNJTASLUOY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

1-Chloro-2-propanol is formed as an intermediate during the degradation of meso-bis-(1-chloro-2-propyl)ether by Rhodococcus sp. strain DTB.

Application

1-Chloro-2-propanol has been used as:
  • chemical intermediate for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycol
  • as α,β-halohydrin standard during the enzymatic synthesis of α,β-halohydrins from gaseous alkenes

Pictograms

FlameSkull and crossbones
GHS02,GHS06

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

125.6 °F - closed cup

Flash Point(C)

52 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Leif-Alexander Garbe et al.
FEMS microbiology ecology, 55(1), 113-121 (2006-01-20)
Rhodococcus sp. strain DTB (DSM 44534) was grown on a mixture of (R,R)-, (S,S)- and meso-bis-(1-chloro-2-propyl) ether (BCPE) as the sole source of carbon and energy. During BCPE degradation 1'-chloro-2'-propyl-3-chloro-2-prop-1-enyl-ether (DVE), 1-chloro-2-propanol and chloroacetone intermediates were formed. The BCPE or
J Geigert et al.
Applied and environmental microbiology, 45(2), 366-374 (1983-02-01)
The enzymatic synthesis of alpha,beta-halohydrins from gaseous alkenes is described. The enzymatic reaction required an alkene, a halide ion, dilute hydrogen peroxide, and a haloperoxidase enzyme. A wide range of gaseous alkenes were suitable for this reaction, including those containing
A R Jones et al.
Xenobiotica; the fate of foreign compounds in biological systems, 10(11), 835-846 (1980-11-01)
1. The metabolism of 1,2-dichloropropane in the rat has been investigated. The major urinary metabolite has been isolated and identified as N-acetyl-S-(2-hydroxypropyl)cysteine. Two minor metabolites of 1,2-dichloropropane have been identified as beta-chlorolactate and N-acetyl-S-(2,3-dihydroxypropyl)cysteine. 2. The fate of 1-chloro-2-hydroxypropane, a
Reproductive toxicology. 1-Chloro-2-propanol.
Environmental health perspectives, 105 Suppl 1, 291-292 (1997-02-01)
Li Sun et al.
Journal of nanoscience and nanotechnology, 11(3), 2283-2286 (2011-04-01)
In this paper, we report a facile method to fabricate silver nanowire array electrodes (SNAE) with ultra-high detection sensitivity to chloropropanol in the aqueous solution. Silver nanowire arrays were assembled in conventional anodic alumina membranes (AAM) by electrochemical deposition. Subsequently
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service