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Key Documents

SRP5144

Sigma-Aldrich

Stathmin, His tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

C1orf215, FLJ32206, LAP18, Lag, MGC138869, MGC138870, OP18, PP17, PP19, PR22, SMN, STMN1

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About This Item

CAS Number:
956166-50-0
UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

mol wt

~19 kDa

NCBI accession no.

BC014353

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... STMN1(3925)

Physical form

Supplied in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H360D

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
R111-2

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The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network.
Gavet O
Journal of Cell Science, 111(Pt 22), 3333-3346 (1998)
STMN1 overexpression correlates with biological behavior in human cutaneous squamous cell carcinoma.
Li X
Pathology Research and Practice, 211(11), 816-823 (2015)
Covalent modification of stathmin by CCNU determined by FTMS analysis of modified proteins and tryptic peptides.
Wu WW
Biochemical and Biophysical Research Communications, 367(1), 7-13 (2008)
A Sobel
Trends in biochemical sciences, 16(8), 301-305 (1991-08-01)
Stathmin is a ubiquitous, phylogenetically conserved protein present in the cytoplasm of cells in a variety of unphosphorylated and phosphorylated forms. Its expression and phosphorylation are regulated throughout development and in response to extracellular signals regulating cell proliferation, differentiation and
Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro.
Velasco, et al.
Communications biology, 6, 488-488 (2023)
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