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SAB2501055

Sigma-Aldrich

Anti-TRABID/ZRANB1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-DKFZp762P2216, Anti-RAN-binding domain containing 1, Anti-TRABID, Anti-TRAF-binding protein domain

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

canine, human, mouse, pig, bovine

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... ZRANB1(54764)

General description

Zinc finger RANBP2-type containing 1 (ZRANB1) is a deubiquitinase which is part of the OTU family. It possesses an ovarian tumor (OTU) catalytic domain. This 708 amino acid protein consists of three amino-terminal Npl4-like zinc finger (NZF) domains. The ZRANB1 gene is localized on human chromosome 10q26.13.

Immunogen

Peptide with sequence KWLDRYRQIRPCTS from the C Terminus of the protein sequence according to NP_060050.2.

Biochem/physiol Actions

Zinc finger RANBP2-type containing 1 (ZRANB1) is a positive modulator of Wnt signaling pathways. It hydrolyzes K29- and K33-linked ubiquitin chains.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains.
Licchesi JD
Nature Structural and Molecular Biology (2011)
K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin.
Kristariyanto YA
Molecular Cell (2015)
Rare copy number variation in cerebral palsy
Gai McMichael
European Journal of Human Genetics (2014)

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