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Key Documents

Q0259

Sigma-Aldrich

Q-Ceramic HyperD® F

50 μm mean particle size

Synonym(s):

HyperD® ceramic ion exchangers

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About This Item

UNSPSC Code:
23201100

mean particle size

50 μm

capacity

>0.20 meq/mL

storage temp.

2-8°C

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Application

Ceramic HyperD media are used in protein chromatography and affinity chromatography. Ceramic HyperD media have been used in the development of a capture step of a human recombinant F(ab′)(2) produced and expressed in baculovirus-infected cells and to identify whey proteins as a model system for chromatographic separation of proteins.

Features and Benefits

HyperD media are highly porous, rigid ceramic beads filled with a functionalized hydrophilic gel. The rigid bead allows extremely high linear flow rates without bed compression. The hydrogel exchanges throughout its volume, not just on the surface. And the media do not change volume due to changes in pH or ionic strength.
The supports are stable in commonly used solvents and alkaline or acid environments. Supplied as aqueous suspensions in 1 M NaCl with 20% ethanol to inhibit bacterial growth.

Legal Information

HyperD is a registered trademark of Pall Corporation

Pictograms

FlameCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

95.0 °F

Flash Point(C)

35 °C


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John Yee et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27(17), 2787-2792 (2009-05-06)
There are no reliable blood biomarkers to detect early lung cancer. We used a novel strategy that allows discovery of differentially present proteins against a complex and variable background. Mass spectrometry analyses of paired pulmonary venous-radial arterial blood from 16
Sandrine Delbosc et al.
Molecular medicine (Cambridge, Mass.), 14(7-8), 383-394 (2008-05-23)
Hypertension represents one of the main risk factors for vascular diseases. Genetic susceptibility may influence the rate of its development and the associated vascular remodeling. To explore markers of hypertension-related morbidity, we have used surface-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass
Kate Gilbert et al.
Methods in molecular biology (Clifton, N.J.), 264, 259-269 (2004-03-17)
Protein-expression profiling of serum is a common approach to the discovery of potential diagnostic and therapeutic markers of disease. Like any other proteome, the serum proteome is characterized by protein expression across a large dynamic range. This single facet requires
Cleophas M Kyama et al.
Fertility and sterility, 95(4), 1338-1343 (2010-08-31)
To test the hypothesis that specific proteins and peptides are expressed differentially in eutopic endometrium of women with and without endometriosis and at specific stages of the disease (minimal, mild, moderate, or severe) during the secretory phase. Patients with endometriosis
Qing Yang et al.
Pediatric research, 66(1), 11-16 (2009-03-17)
Preterm labor (PTL) is frequently associated with inflammation. We hypothesized that biomarkers during pregnancy can identify pregnancies most at risk for development of PTL. An inflammation-induced mouse model of PTL was used. Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry was used

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