Inactivated refers to rendering something non-viable or dead. Researchers who purchase products from this category typically seek to work with a complete bacterium (intact DNA) but without dealing with a live bacterium. Certain labs seek to understand how to deactivate the bacterium without harming its DNA, enabling them to obtain the product internally. As a result, the inactivation method is kept confidential. Sterility testing is conducted to confirm that complete inactivation has been accomplished.
MBD0009
Inactivated Porphyromonas gingivalis
Suitable for DNA extraction, PCR, sequencing, next generation sequencing, >10^8 bacteria/vial
Synonym(s):
Standard DNA
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About This Item
UNSPSC Code:
41105500
NACRES:
NA.51
Pricing and availability is not currently available.
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Quality Level
form
powder
concentration
>10^8 bacteria/vial
technique(s)
DNA extraction: suitable
DNA sequencing: suitable
PCR: suitable
shipped in
dry ice
storage temp.
−20°C
General description
Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses. Inactivated Prophyromonas gingivalis can serve as standard for benchmarking the performance along the workflow of microbiomics or meta-genomics analyses and as a tool to increase reproducibility and allow comparison of results obtained by different labs. Porphyromonas gingivalis, is a gram negative bacterium which is an etiologic agent of adult periodontitis, a chronic inflammatory disease characterized by the destruction of the supportive tissue surrounding teeth. Studies have shown that LPS from P. gingivalis plays an important role in this disease. The association of the oral microbiota, including P. gingivalis, with various pathological states has been reported. These include development of Alzheimer’s disease, role in oral cancers, preterm birth and rheumatoid arthritis.
Read here how to use our standards to ensure data integrity for your microbiome research.
Read here how to use our standards to ensure data integrity for your microbiome research.
Application
Inactivated bacteria are provided at >10^8 bacteria/vial as lyophilized powder. It is recommended to avoid freeze thaw cycles of this product.
Physical form
Powder -The inactivated bacteria are provided at >10^8 bacteria/vial as lyophilized powder
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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