G4274
Globoside from human erythrocytes
≥95%
Synonym(s):
Globotetraosylceramide
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biological source
human erythrocytes
Assay
≥95%
form
film
functional group
amide
hydroxyl
shipped in
ambient
storage temp.
−20°C
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Tetsuya Okuda et al.
Glycoconjugate journal, 27(2), 287-296 (2010-01-19)
In several vascular inflammatory reactions (i.e. immunity and thrombosis) inflammatory mediators lead to the activation of vascular endothelial cells (EC). To date, a number of functional molecules induced on the surface of activated-EC have been identified. We report here that
Anne Müsken et al.
Rapid communications in mass spectrometry : RCM, 24(7), 1032-1038 (2010-03-10)
Glycosphingolipids (GSLs) play key roles in the manifestation of infectious diseases as attachment sites for pathogens. The thin-layer chromatography (TLC) overlay assay represents one of the most powerful approaches for the detection of GSL receptors of microorganisms. Here we report
Kiyotaka Nishikawa
Archivum immunologiae et therapiae experimentalis, 59(4), 239-247 (2011-06-07)
Infection with Shiga toxin (Stx)-producing Escherichia coli (STEC), including O157:H7, causes bloody diarrhea and hemorrhagic colitis in humans, occasionally resulting in fatal systemic complications, such as neurological damage and hemolytic-uremic syndrome. Because Stx is a major virulence factor of the
Tetsuya Okuda
International journal of molecular sciences, 21(10) (2020-05-28)
Glycosphingolipids containing very-long-chain fatty acids (VLCFAs) regulate several immune responses, such as cytokine production, immune signaling, and antibody induction. We previously reported that stimulation with an inflammatory mediator, TNF-α, promotes the expression of glycosphingolipids in vascular endothelial cells. The major
Y Song et al.
The Journal of biological chemistry, 273(5), 2517-2525 (1998-02-28)
Undifferentiated human embryonal carcinoma cells are characterized by high expression of lactoneotetraosylceramide (nLc4), globoside (Gb4), and extended globo-series glycosphingolipids (GSLs) termed "stage-specific embryonic antigens 3 and 4" (SSEA-3 and -4). Expression of these GSLs declines in association with a decline
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