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55496

Sigma-Aldrich

Hydroxyapatite

′high resolution′

Synonym(s):

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

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About This Item

Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
1306-06-5
Molecular Weight:
502.31
EC Number:
215-145-7
MDL number:
MFCD00010904
UNSPSC Code:
12352200
PubChem Substance ID:
57651499

capacity

≥1.2 mg/g, dry material binding capacity (DNA)
 ≥15 mg/g, dry material binding capacity (BSA)

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Other Notes

DNA purification; Analysis of DNA damage; Stabilization of double-standard DNA

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBL0870V
BCBB4869V
BCBD4972V
BCBB4869
BCBB4505

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A hydroxylapatite batch assay for quantitation of cellular DNA damage.
P M Kanter et al.
Analytical biochemistry, 97(1), 77-84 (1979-08-01)
Rapid isolation of mouse DNA from cells in tissue culture.
W Meinke et al.
Analytical biochemistry, 58(1), 82-88 (1974-03-01)
The nucleic acid-hydroxylapatite interaction. I. Stabilization of native double-stranded deoxyribonucleic acid by hydroxylapatite.
H G Martinson
Biochemistry, 12(1), 139-145 (1973-01-02)
Sophie E P New et al.
Circulation research, 113(1), 72-77 (2013-04-26)
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute
H S Alghamdi et al.
Journal of dental research, 92(11), 982-988 (2013-09-24)
Osteoporotic conditions are anticipated to affect the osseointegration of dental implants. This study aimed to evaluate the effect of a radiofrequent magnetron-sputtered calcium phosphate (CaP) coating on dental implant integration upon installment in the femoral condyles of both healthy and
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