Anaesthesia and intensive care, 41(2), 175-183 (2013-03-28)
Sepsis remains as a leading cause of death in critically ill patients. Unfortunately, there have been very few successful specific therapeutic agents that can significantly reduce the attributable mortality and morbidity of sepsis. Developing novel therapeutic strategies to improve outcomes
Science (New York, N.Y.), 340(6140), 1567-1570 (2013-07-03)
The textbook description of mitochondrial respiratory complexes (RCs) views them as free-moving entities linked by the mobile carriers coenzyme Q (CoQ) and cytochrome c (cyt c). This model (known as the fluid model) is challenged by the proposal that all
The importance of dietary polyunsaturated fatty acids (PUFAs) in the reduction of cardiovascular disease has been recognized for many years. Docosahexaenoic acid (22:6n3, DHA) is an n-3 PUFA known to affect numerous biological functions and provide cardioprotection; however, the exact
The retinoblastoma protein gene RB-1 is mutated in one-third of human tumors. Its protein product, pRB (retinoblastoma protein), functions as a transcriptional coregulator in many fundamental cellular processes. Here, we report a nonnuclear role for pRB in apoptosis induction via
Journal of biomedical nanotechnology, 9(3), 409-416 (2013-04-30)
An amperometric biosensor for determination of Cytochrome c (Cyt c) was fabricated by immobilizing Cytochrome c oxidase (COx) onto nickel oxide nanoparticles (NiO-NPs) decorated carboxylated multiwalled carbon nanotubes/polyaniline (NiO-NPs/cMWCNT/PANI) film electrodeposited on the surface of a gold (Au) electrode. The
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